Table 2

Proteins that showed differential expression after RNAi targeting MBD1

Spot No.
Accession No.
Protein Name
Protein MW
Protein pI
Protein Score
Fold change

429
gi| 5174735
tubulin, beta, 2
49808
4.79
68
↑4.05
896
gi| 5902076
splicing factor, arginine/serine-rich 1 isoform 1
27727.8
10.37
191
↑3.52
384
gi| 1208427
ER-60 protease
56760.8
5.98
140
↑4.09
363
gi| 20070125
prolyl 4-hydroxylase, beta subunit precursor
57058.6
4.76
70
↑4.06
922
gi| 20149675
EF hand domain family, member D2
26680.5
5.15
120
Only in BxPC-3/MBD1-siRNA
218
gi| 14916999
78 kDa glucose-regulated protein precursor (GRP 78) (Heat shock 70 kDa protein 5)
72377.5
5.07
249
↓4.02
1023
gi| 6048243
TOLLIP protein
23206.7
5.68
116
Only in BxPC-3/ vector
649
gi| 48257068
HSPA8 protein
64633.1
5.36
95
Only in BxPC-3/ vector
391
gi| 62414289
vimentin
53619.1
5.06
334
↓20.64
1177
gi| 5031851
stathmin 1
17291.9
5.76
90
↓3.48
1264
gi| 14719392
cofilin2
18724.8
7.66
74
Only in BxPC-3/ vector
640
gi| 55958543
heterogeneous nuclear ribonucleoprotein K
33954.7
5.54
74
Only in BxPC-3/ vector
557
gi| 4503519
eukaryotic translation initiation factor 3, subunit 5
37540.1
5.24
131
Only in BxPC-3/ vector
703
gi| 141623
Zinc finger protein ZFP-36
66639.8
8.99
65
Only in BxPC-3/ vector

Liu et al. BMC Cancer 2008 8:121   doi:10.1186/1471-2407-8-121