Figure 4.

TLR3 blockade attenuates poly I:C-improved tumor apoptosis. Hela cells or MCA38 cells were treated with purified anti-human TLR3 antibody or anti-mouse TLR3 antibody at the concentration of 10 μg/ml for 4 hours before being stimulated with poly I:C (100 μg/ml)/CHX (1.5 μg/ml) for 12 hours. Apoptosis were determined as above. The data is presented as the mean ± SD.