Table 2 |
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|
Differentially expressed Fibromatosis and Desmoplastic response genes in the MAM-1 Transcriptome |
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|
Agilent Accession |
Genbank Accession |
Ratio of MAM-1 vs. Bam1a |
p-value (n = 3) |
Gene Description and Symbol |
Reference |
|
|
|||||
|
A_51_P162272 |
5.95 |
2.58E-03 |
Mus musculus wingless-related MMTV integration site 5A (Wnt5a), mRNA [NM_009524] |
West |
|
|
A_51_P390804 |
125.00 |
8.89E-06 |
Mus musculus WNT1 inducible signaling pathway protein 2 (Wisp2), mRNA [NM_016873] |
West |
|
|
A_51_P220343 |
16.66 |
4.06E-06 |
Mus musculus WNT1 inducible signaling pathway protein 1 (Wisp1), mRNA [NM_018865] |
West |
|
|
A_52_P658611 |
19.92 |
4.09E-03 |
Mus musculus procollagen, type I, alpha 1 (Col1a1), mRNA [NM_007742] |
West, Iacobuzio-Donahue |
|
|
A_52_P525107 |
187.97 |
1.12E-05 |
Mus musculus procollagen, type I, alpha 1 (Col1a1), mRNA [NM_007742] |
West, Iacobuzio-Donahue |
|
|
A_51_P377094 |
37.17 |
9.02E-08 |
Mus musculus procollagen, type I, alpha 1 (Col1a1), mRNA [NM_007742] |
West, Iacobuzio-Donahue |
|
|
A_51_P414637 |
168.63 |
7.15E-06 |
Mus musculus procollagen, type V, alpha 1 (Col5a1), mRNA [NM_015734] |
West |
|
|
A_52_P684242 |
4.93 |
7.45E-05 |
Mus musculus procollagen, type III, alpha 1 (Col3a1), mRNA [NM_009930] |
West |
|
|
A_51_P515605 |
94.34 |
1.67E-09 |
Mus musculus procollagen, type III, alpha 1 (Col3a1), mRNA [NM_009930] |
West |
|
|
A_51_P474496 |
12.21 |
6.30E-08 |
Mus musculus procollagen, type VI, alpha 1 (Col6a1), mRNA [NM_009933] |
West |
|
|
A_51_P502132 |
7.69 |
1.96E-07 |
Mus musculus matrix metalloproteinase 23 (Mmp23), mRNA [NM_011985] |
West |
|
|
A_51_P269166 |
13.33 |
1.11E-02 |
Mus musculus matrix metalloproteinase 19 (Mmp19), mRNA [NM_021412] |
West |
|
|
A_51_P293087 |
4.76 |
7.12E-06 |
Mus musculus matrix metalloproteinase 11 (Mmp11), mRNA [NM_008606] |
West |
|
|
A_51_P404077 |
3.45 |
3.09E-06 |
Mus musculus frizzled homolog 2 (Drosophila) (Fzd2), mRNA [NM_020510] |
West |
|
|
A_52_P597634 |
4.55 |
5.25E-07 |
Mus musculus frizzled homolog 1 (Drosophila) (Fzd1), mRNA [NM_021457] |
West |
|
|
A_52_P224801 |
130.03 |
1.47E-03 |
Mus musculus fibrillin 1 (Fbn1), mRNA [NM_007993] |
West |
|
|
A_51_P467224 |
240.38 |
8.77E-05 |
Mus musculus fibrillin 1 (Fbn1), mRNA [NM_007993] |
West |
|
|
A_52_P220176 |
20.88 |
3.70E-02 |
Mus musculus dickkopf homolog 3 (Xenopus laevis) (Dkk3), mRNA [NM_015814] |
West |
|
|
A_52_P489295 |
4.22 |
2.72E-05 |
Mus musculus a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 1 (Adamts1), mRNA [NM_009621] |
West |
|
|
A_52_P213932 |
3.10 |
1.94E-05 |
Mus musculus a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 1 (Adamts1), mRNA [NM_009621] |
West |
|
|
A_52_P280044 |
16.21 |
1.63E-05 |
Mus musculus a disintegrin and metalloproteinase domain 19 (meltrin beta) (Adam19), mRNA [NM_009616] |
West |
|
|
A_51_P267447 |
10.35 |
8.95E-04 |
Mus musculus a disintegrin and metalloproteinase domain 19 (meltrin beta) (Adam19), mRNA [NM_009616] |
West |
|
|
A_52_P290457 |
33.11 |
4.05E-03 |
Mus musculus a disintegrin and metalloproteinase domain 12 (meltrin alpha) (Adam12), mRNA [NM_007400] |
West, Peduto |
|
|
A_51_P510882 |
9.35 |
1.38E-03 |
Mus musculus a disintegrin and metalloproteinase domain 12 (meltrin alpha) (Adam12), mRNA [NM_007400] |
West, Peduto |
|
|
A_51_P350817 |
38.46 |
1.29E-04 |
Mus musculus calponin 1 (Cnn1), mRNA [NM_009922] |
West |
|
|
A_52_P599578 |
1.24 |
1.03E-02 |
Mus musculus caldesmon 1 (Cald1), mRNA [NM_145575] |
West |
|
|
A_51_P357573 |
1.25 |
3.07E-02 |
Mus musculus caldesmon 1 (Cald1), mRNA [NM_145575] |
West |
|
|
A_51_P157042 |
14.33 |
1.71E-04 |
Mus musculus connective tissue growth factor (Ctgf), mRNA [NM_010217] |
West |
|
|
A_51_P124748 |
0.45 |
7.08E-04 |
Mus musculus transforming growth factor, beta 3 (Tgfb3), mRNA [NM_009368] |
West |
|
|
A_51_P212754 |
11.76 |
1.54E-03 |
Mus musculus transforming growth factor, beta induced (Tgfbi), mRNA [NM_009369] |
Iacobuzio-Donahue |
|
|
A_51_P472292 |
65.79 |
6.80E-09 |
Mus musculus insulin-like growth factor binding protein 7 (Igfbp7), mRNA [NM_008048] |
Iacobuzio-Donahue |
|
|
A_51_P110301 |
4.59 |
3.95E-05 |
Mus musculus complement component 3 (C3), mRNA [NM_009778] |
Iacobuzio-Donahue |
|
|
A_51_P218774 |
2.74 |
9.21E-04 |
Mus musculus regulator of G-protein signalling 10 (Rgs10), mRNA [NM_026418] |
Iacobuzio-Donahue |
|
|
A_51_P224843 |
2.84 |
2.24E-03 |
Mus musculus thymosin, beta 4, X chromosome (Tmsb4x), mRNA [NM_021278] |
Iacobuzio-Donahue |
|
|
A_51_P111210 |
1.10 |
1.45E-01 |
Mus musculus SMC4 structural maintenance of chromosomes 4-like 1 (yeast) (Smc4l1), mRNA [NM_133786] |
Iacobuzio-Donahue |
|
|
A_52_P101852 |
27.25 |
1.90E-07 |
Mus musculus secreted acidic cysteine rich glycoprotein (Sparc), mRNA [NM_009242] |
Iacobuzio-Donahue |
|
|
A_51_P431087 |
67.11 |
1.96E-08 |
Mus musculus secreted acidic cysteine rich glycoprotein (Sparc), mRNA [NM_009242] |
Iacobuzio-Donahue |
|
|
A_51_P452876 |
7.46 |
3.48E-06 |
Mus musculus adenylate kinase 1 (Ak1), mRNA [NM_021515] |
Iacobuzio-Donahue |
|
|
A_51_P149562 |
6.13 |
1.52E-04 |
Mus musculus amyloid beta (A4) precursor protein-binding, family B, member 2 (Apbb2), mRNA [NM_009686] |
Iacobuzio-Donahue |
|
|
A_52_P49250 |
0.86 |
4.40E-03 |
Mus musculus v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) (Erbb2), transcript variant 2, mRNA [NM_010152] |
Iacobuzio-Donahue |
|
|
A_51_P216179 |
0.54 |
3.14E-03 |
Mus musculus v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) (Erbb2), transcript variant 2, mRNA [NM_010152] |
Iacobuzio-Donahue |
|
|
A_51_P341736 |
2.74 |
1.93E-04 |
Mus musculus matrix metalloproteinase 2 (Mmp2), mRNA [NM_008610] |
Wang, Singer |
|
|
A_51_P258529 |
15.77 |
3.73E-05 |
Mus musculus peripheral myelin protein (Pmp22), mRNA [NM_008885] |
Kunz-Schughart |
|
|
A_51_P213359 |
23.70 |
1.46E-07 |
Mus musculus hyaluronan synthase 2 (Has2), mRNA [NM_008216] |
Li |
|
|
A_52_P582374 |
0.04 |
5.59E-03 |
Mus musculus epithelial stromal interaction 1 (breast) (Epsti1), transcript variant b, mRNA [NM_178825] |
Gudjonsson |
|
|
A_51_P376050 |
0.03 |
2.78E-03 |
Mus musculus epithelial stromal interaction 1 (breast) (Epsti1), transcript variant a, mRNA [NM_029495] |
Gudjonsson |
|
|
A_51_P127681 |
3.62 |
1.28E-07 |
Mus musculus chloride intracellular channel 4 (mitochondrial) (Clic4), mRNA [NM_013885] |
Suh, Ronnov-Jessen |
|
|
A_51_P392687 |
25.000 |
5.47E-04 |
Mus musculus vimentin (Vim), mRNA [NM_011701] |
||
|
A_52_P56471 |
4.35 |
8.57E-06 |
Mus musculus epidermal growth factor receptor (Egfr), transcript variant 2, mRNA [NM_007912] |
||
|
A_51_P392242 |
4.17 |
1.10E-05 |
Mus musculus epidermal growth factor receptor (Egfr), transcript variant 2, mRNA [NM_007912] |
||
|
A_52_P674338 |
7.14 |
1.90E-03 |
Mus musculus epidermal growth factor receptor (Egfr), transcript variant 1, mRNA [NM_207655] |
||
|
A_52_P106259 |
11.56 |
2.06E-05 |
Mus musculus epidermal growth factor receptor (Egfr), transcript variant 1, mRNA [NM_207655] |
||
|
A_51_P414813 |
0.61 |
3.13E-03 |
Mus musculus v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) (Erbb3), mRNA [NM_010153] |
||
|
A_51_P342050 |
0.58 |
3.28E-02 |
Mus musculus v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) (Erbb3), mRNA [NM_010153] |
||
|
A_52_P420504 |
17.18 |
7.97E-05 |
Mus musculus actin, alpha 2, smooth muscle, aorta (Acta2), mRNA [NM_007392] |
||
|
A_52_P210078 |
101.94 |
6.74E-05 |
Mus musculus actin, alpha 2, smooth muscle, aorta (Acta2), mRNA [NM_007392] |
||
|
A_51_P103396 |
0.260 |
2.69E-04 |
Mus musculus keratin complex 2, basic, gene 18 (Krt2-18), mRNA [NM_016879] |
||
|
A_51_P356642 |
5.550 |
7.53E-06 |
Mus musculus keratin complex 1, acidic, gene 19 (Krt1-19), mRNA [NM_008471] |
||
|
A_51_P482128 |
2.760 |
3.01E-04 |
Mus musculus keratin complex 1, acidic, gene 15 (Krt1-15), mRNA [NM_008469] |
||
|
A_51_P118225 |
0.028 |
7.55E-04 |
Mus musculus junction adhesion molecule 4 (Jam4), mRNA [NM_028078] |
||
|
A_51_P358354 |
30.030 |
2.21E-06 |
Mus musculus junction adhesion molecule 3 (Jam3), mRNA [NM_023277] |
||
|
A_52_P374846 |
19.120 |
9.97E-04 |
Mus musculus junction adhesion molecule 2 (Jam2), mRNA [NM_023844] |
||
|
A_51_P418375 |
10.256 |
8.90E-04 |
Mus musculus junction adhesion molecule 2 (Jam2), mRNA [NM_023844] |
||
|
A_52_P93974 |
0.316 |
1.46E-02 |
Mus musculus integrin beta 6 (Itgb6), mRNA [NM_021359] |
||
|
A_52_P459521 |
0.261 |
3.06E-05 |
Mus musculus integrin beta 4 (Itgb4), transcript variant 3, mRNA [NM_001005607] |
||
|
A_51_P382970 |
25.125 |
3.19E-02 |
Mus musculus integrin alpha 9 (Itga9), mRNA [NM_133721] |
||
|
A_52_P413034 |
2.985 |
2.73E-02 |
Mus musculus integrin alpha 7 (Itga7), mRNA [NM_008398] |
||
|
A_51_P181671 |
3.401 |
4.71E-03 |
Mus musculus integrin alpha 7 (Itga7), mRNA [NM_008398] |
||
|
A_52_P364140 |
30.030 |
1.76E-06 |
Mus musculus integrin alpha 5 (fibronectin receptor alpha) (Itga5), mRNA [NM_010577] |
||
|
A_52_P223495 |
0.304 |
4.71E-02 |
Mus musculus integrin alpha 4 (Itga4), mRNA [NM_010576] |
||
|
A_51_P515056 |
0.316 |
9.78E-05 |
Mus musculus integrin alpha 3 (Itga3), mRNA [NM_013565] |
||
|
A_51_P230405 |
0.260 |
5.62E-05 |
Mus musculus integrin alpha 3 (Itga3), mRNA [NM_013565] |
||
|
A_52_P612019 |
3.300 |
3.55E-02 |
Mus musculus integrin alpha 2 (Itga2), mRNA [NM_008396] |
||
|
|
|||||
|
aAverage fold difference is the ratio (n = 3, p value cutoff > .05) compares the expression levels of MAM-1 RNA normalized to Universal Mouse RNA to Bam1a RNA normalized to Universal Mouse RNA. RNA from MAM-1 or Bam1a was labeled in red color (cy5), universal RNA is labeled in green (cy3). Three independent RNA preparations per condition were analyzed on three separate chips and averaged; a confidence cutoff of >0.95 was used for the raw values of red/green before normalization. The fold change (**MAM-1 or Bam1a/**Universal Mouse) = Normalized ratio value(cy5/cy3). P-values are for the comparisons between the MAM-1 and Bam1a. The references associated with specific genes are indicated in the text of the manuscript. |
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|
Piechocki BMC Cancer 2008 8:119 doi:10.1186/1471-2407-8-119 |
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