Table 1

Clinico-pathological characteristics of the patients



analyzed
Patients characteristics
all trial patients B 1/2 (n = 1399)
NHL patients (n = 311)
DLBCL patients (n = 205)

Age Median; yr (range) 75)
60 (18–75)
62 (23–75)
61 (23–75)
Sex



     male
789 (56%)
175 (56%)
115 (56%)
     female
610 (44%)
136 (44%)
90 (44%)
International Prognostic Index (IPI)



     Low (0,1)
840 (60%)
176 (57%)
118 (58%)
     Low intermediate (2)
250 (18%)
62 (20%)
42 (20%)
     High intermediate (3)
170 (12%)
46 (15%)
31 (15%)
     High (4,5)
139 (10%)
27 (9%)
14 (7%)
Risk Age



     Age ≤ 60 yrs
710 (51%)
143 (46%)
98 (48%)
     Age > 60 yrs
689 (49%)
168 (54%)
107(52%)
Risk extranodal involvement



     ≤ 1 ex. involvement
1123 (80%)
254 (82%)
174(85%)
     > 1 ex. involvement
276 (20%)
57 (18%)
31(15%)
Risk ECOG



     ECOG 0,1
1236 (88%)
273 (88%)
178(87%)
     ECOG 2–4
163 (12%)
38 (12%)
27(13%)
Risk Stage



     Stage I, II
832 (59%)
191 (61%)
134(65%)
     Stage III-IV
567 (41%)
120 (39%)
71(35%)
Risk LDH



     LDH ≤ ONW
1083 (77%)
241 (77%)
160(78%)
     LDH > ONW
316 (23%)
70 (23%)
45(22%)
Bulky tumor (7.5 cm or larger)
467 (33%)
90 (29%)
62(30%)

Bittenbring et al. BMC Cancer 2008 8:116   doi:10.1186/1471-2407-8-116