Table 1

Primary information of selected SNPs of the XPC gene

Gene [accession no.] and locus

NCBI rs no.

location

AAa change

Base change

MAFb of cases

MAFb of controls

MAFb in EGPc

MAFb in HapMapd

% genotyped


XPC [NCBI: AY131066] 3p25.1

rs3731055

000603, close to 5'UTR

G > A

0.25

0.27

0.07

---

96.6

rs2607775

000947, close to 5'UTR

C > G

0.04

0.04

0.35

---

98.3

rs3729587

012413, intron 5

C > G

0.11

0.11

0.35

---

92.5

rs2228000

021151, exon 9

A499V

C > T

0.33

0.32

0.24

0.30

98.2

rs2228001

033512, exon 16

K939Q

A > C

0.38

0.36

0.34

0.38

98.2


aAA: amino acid.

bMAF: Minor allele frequencies.

cEGP: US environmental Genome Project SNP database.

dHapMap: For Chinese included in the International HapMap Project.

Bai et al. BMC Cancer 2007 7:81   doi:10.1186/1471-2407-7-81

Open Data