Table 1

Primary information of selected SNPs of the XPC gene

Gene [accession no.] and locus

NCBI rs no.

location

AA^a change

Base change

MAF^b of cases

MAF^b of controls

MAF^b in EGP^c

MAF^b in HapMap^d

% genotyped

XPC [NCBI: AY131066] 3p25.1

rs3731055

000603, close to 5'UTR

G > A

0.25

0.27

0.07

---

96.6

rs2607775

000947, close to 5'UTR

C > G

0.04

0.04

0.35

---

98.3

rs3729587

012413, intron 5

C > G

0.11

0.11

0.35

---

92.5

rs2228000

021151, exon 9

A499V

C > T

0.33

0.32

0.24

0.30

98.2

rs2228001

033512, exon 16

K939Q

A > C

0.38

0.36

0.34

0.38

98.2

^aAA: amino acid.

^bMAF: Minor allele frequencies.

^cEGP: US environmental Genome Project SNP database.

^dHapMap: For Chinese included in the International HapMap Project.

Bai et al. BMC Cancer 2007 7:81   doi:10.1186/1471-2407-7-81