|
Risk of colon cancer and HRT use: Ever-use of HRT vs. never-use. |
|||
| e-case1 |
e-ctrl.1 |
Adj. OR (95% CI) |
|
|
|
|||
| Ever HRT |
150 |
562 |
0.97 (0.71–1.32) |
| Duration of use2,3 |
|||
| 1–4 yrs |
22 |
130 |
0.65 (0.37–1.16) |
| 5–9 yrs |
41 |
180 |
1.06 (0.67–1.68) |
| 10+ yrs |
45 |
175 |
0.87 (0.53–1.41) |
| Time since first use2,3 |
|||
| 1–4 yrs |
41 |
148 |
1.04 (0.66–1.66) |
| 5–9 yrs |
46 |
193 |
0.99 (0.64–1.52) |
| 10–14 yrs |
36 |
133 |
1.04 (0.65–1.69) |
| 15+ yrs |
27 |
88 |
0.79 (0.45–1.39) |
| Time since last use2,3 |
|||
| < 1 yr/current use |
136 |
496 |
1.00 (0.74–1.38) |
| 1–2 yrs |
8 |
43 |
0.72 (0.31–1.69) |
| 3–4 yrs |
5 |
22 |
0.85 (0.29–2.50) |
| 5+ yrs |
1 |
1 |
n.d.4 |
|
1 e-case, e-ctrl = number of observations for exposed cases or exposed controls respectively. 2 time variables were rounded 3 no significant trend with increasing time 4 n.d. = no data Conditional logistic regression analysis [odds ratios (OR) and 95% confidence intervals]; adjustment for BMI, family history of colon cancer, childbearing history, age at first live birth, duration of breast-feeding, age at menarche, ever OC use, education. Index dates 0.5 = exposure information was not considered 0.5 years prior to cancer diagnosis. | |||
Dinger et al. BMC Cancer 2007 7:76 doi:10.1186/1471-2407-7-76 |
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