|
Bortezomib and celecoxib cohort dosing schedules |
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| Cohorts |
Bortezomib (mg/m2) |
Bortezomib days of administration |
Celecoxib (mg PO bid) |
|
|
|||
| Level 1 |
1.0 |
1, 8, 15, 22, 29 q42 days |
200 |
| Level 2 |
1.0 |
1, 4, 8, 11 q21 days |
200 |
| Level 3 |
1.3 |
1, 8, 15, 22, 29 q42 days |
300 |
| Level 4 |
1.3 |
1, 4, 8, 11 q21 days |
300 |
| Level 5 |
1.6 |
1, 8, 15, 22, 29 q42 days |
400 |
| Level 6 |
1.3 |
1, 4, 8, 11 q21 days |
400 |
Hayslip et al. BMC Cancer 2007 7:221 doi:10.1186/1471-2407-7-221 |
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