|
Cox multivariate regression analysis: MDR-1 expression (score > 1 vs no expression). |
|
| Co-variables |
Significance (p) |
|
|
|
| Sex |
0,680 |
| Age* |
0,893 |
| Death from disease |
0,016 |
| Grading* |
0,627 |
| Tumour Size* |
0,842 |
| Multicentric Pattern of Growth |
0,380 |
| Thrombosis of caval vein |
0,372 |
| Necrosis |
0,378 |
| Adjuvant Therapy |
0,336 |
|
We have considered MDR-1 as state variable in correlation with different clinical and histopathological co-variables. The only significant statistical association has been noticed between MDR-1 expression and poorer prognosis (p = 0.016). MDR-1 expression seems to be a prognostic factor independent of adjuvant therapy (no significant p). *: for these co-variables, we have fixed the different cut-off values (≤ 65 years vs > 65 years for Age, G1 vs G2–G3–G4 for Grading, ≤ 7 cm vs > 7 cm as regards Tumour Size). | |
Mignogna et al. BMC Cancer 2006 6:293 doi:10.1186/1471-2407-6-293 |
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