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Dramatic tumour response to pemetrexed single-agent in an elderly patient with malignant peritoneal mesothelioma: a case report

Gianpiero Fasola*, Fabio Puglisi, Alessandro Follador, Marianna Aita, Silvia Di Terlizzi and Ornella Belvedere

Author Affiliations

Dept. of Medical Oncology, University Hospital, P.le S. M. Misericordia, 33100 Udine, Italy

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BMC Cancer 2006, 6:289  doi:10.1186/1471-2407-6-289

Published: 18 December 2006



To date, there is no standard treatment for unresectable malignant peritoneal mesothelioma; either best supportive care or systemic chemotherapy with palliative intent are accepted options.

Case presentation

Here, we report the case of a 79-year old patient with malignant peritoneal mesothelioma who was treated with pemetrexed single-agent and obtained an impressive long-lasting response.


Single-agent pemetrexed is a treatment option for malignant peritoneal mesothelioma in selected elderly patients or in patients with unpaired performance status.