Table 3

Gene data summary.

Gene symbol
Gene description
Function
Summary*

PRSS22
Protease, serine, 22 (Location: 16p13.3)
Serine-type endopeptidase activity
Member of the trypsin family of serine proteases. Enzyme expressed in the airways in a developmentally regulated manner. Serine proteases are involved in blood coagulation, growth factor processing, the digestion of nutrients, and cell migration. Northern hybridization showed that prosemin is expressed predominantly in the pancreas and weakly in the prostate and cerebellum.
RANBP3
RAN binding protein 3 (Location: 19p13.3)
Ran GTPase binding
The RAN GTPase plays an essential role in the transport of macromolecules between the cytoplasm and the nucleus, cell cycle progression, spindle assembly, nuclear organization and nuclear envelope (NE) assembly. RANBP3 (RAN binding protein 3) contains FXFG motifs characteristic of a subgroup of nucleoporins, and a C-terminal domain showing similarity to RANBP1.
TMEM69
Transmembrane protein 69 (Location: 17q21.2)
Unknown
-

*http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene

Solmi et al. BMC Cancer 2006 6:250   doi:10.1186/1471-2407-6-250