Table 3 |
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|
Cox Regression of Risk of Death in Association with MCM2, Ki-67, and Gelsolin in 128 Patients with NSCLC, RPCI, 1995–1999 |
||||
|
Variables |
Crude RR (95%CI) |
P value |
Adjusted RR (95%CI)* |
P value |
|
|
||||
|
MCM2† |
||||
|
Low (n = 49) |
1.00 |
1.00 |
||
|
High (n = 79) |
1.51 (0.94–2.41) |
0.09 |
1.36 (0.84–2.20) |
0.22 |
|
Ki-67‡ |
||||
|
Low (n = 28) |
1.00 |
1.00 |
||
|
High (n = 100) |
0.70 (0.27–1.86) |
0.47 |
0.59 (0.22–1.61) |
0.30 |
|
Gelsolin† |
||||
|
Low (n = 86) |
1.00 |
1.00 |
||
|
High (n = 42) |
1.89 (1.20–2.98) |
0.006 |
1.89 (1.17–3.05) |
0.01 |
|
Gelsolin and MCM2† |
||||
|
Both low (n = 37) |
1.00 |
1.00 |
||
|
GSN low, MCM2 high (n = 49) |
1.34 (0.74–2.42) |
0.33 |
1.34 (0.73–2.45) |
0.34 |
|
GSN high, MCM2 low (n = 12) |
1.62 (0.70–3.73) |
0.26 |
2.08 (0.87–4.98) |
0.10 |
|
GSN high, MCM2 high (n = 30) |
2.59 (1.39–4.80) |
0.003 |
2.32 (1.21–4.45) |
0.01 |
|
|
||||
|
* Adjusted for age, stage, adjuvant chemotherapy, family history of lung cancer, and smoking history. † Results from Cox Proportional Hazards Regression. ‡ Results from time-dependent Cox Regression. |
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|
Yang et al. BMC Cancer 2006 6:203 doi:10.1186/1471-2407-6-203 |
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