Recurrence in skeletal muscle from squamous cell carcinoma of the uterine cervix: a case report and review of the literature
1 Gynecologic Oncology Unit, Catholic University, L.go Gemelli 8, 00168, Rome, Italy
2 Institute of Human Pathology, Catholic University, L.go Gemelli 8, 00168, Rome, Italy
3 Department of Oncology, Catholic University, Contrada Tappino, Campobasso, Italy
BMC Cancer 2006, 6:169 doi:10.1186/1471-2407-6-169Published: 27 June 2006
The occurrence of skeletal muscle metastases is a very rare event. Only two cases of late skeletal muscle recurrence from cervical cancer have been documented until now.
A 38-year old patient, submitted to radical hysterectomy and pelvic lymphadenectomy for a squamous FIGO stage IB1 cervical carcinoma, presented after 76 months with a palpable, and painless swelling on the left hemithorax. MRI showed a nodule located in the context of the intercostal muscles. Pathology revealed the presence of metastasis of squamous cell carcinoma of similar morphology as the primary. On the basis of FDG-PET findings, which excluded other sites of disease, surgical excision of the lesion was performed. The patient was triaged to chemotherapy plus external radiotherapy.
A case of skeletal muscle recurrence from cervical cancer after a very long interval from primary diagnosis is reported. Muscular pain or weakness, or just a palpable mass in a patient with a history of cancer has always to raise the suspicion of muscle metastasis.