Table 5

Association between exposure categories and progesterone receptor expression

Explanatory Variable

Controls

Cases with tumors expressing PR* in 0 to 25% of cells

Cases with tumors expressing PR* in = order 25 to 100% of cells


n

n

OR (95% CI)

n

OR (95% CI)


OC* use

Never

103

15

Referent

33

Referent

Ever

183

31

3.2 (1.3 – 8.0)

64

1.1 (0.6 – 1.9)

HRT* use in post-menopausal women

Never

58

15

Referent

23

Referent

Ever

114

22

0.8 (0.4 – 1.6)

41

0.9 (0.5 – 1.6)

Current menstrual status

Menstruating

114

9

Referent

33

Referent

Post-menopausal

172

37

2.7 (1.2 – 5.8)

64

1.3 (0.8 – 2.1)

Menstrual status 10 years before reference date

Menstruating

158

21

Referent

62

Referent

Post-menopausal

126

23

0.5 (0.2 – 1.5)

35

0.5 (0.2 – 1.0)

Current menstrual status

Menstruating

72

4

Referent

17

Referent

Post-menopausal and not using HRT

58

15

2.4 (1.2 – 5.8)

23

3.1 (1.1 – 8.6)

Menstrual status 10 years before reference date

Menstruating

83

8

Referent

27

Referent

Post-menopausal and not using HRT

46

10

0.3 (0.1 – 2.5)

13

0.8 (0.5 – 1.3)

Smoking status 10 years before reference date

Non-smoker

144

29

Referent

48

Referent

Smoker

142

17

0.5 (0.3 – 1.0)

49

1.0 (0.6 – 1.5)

Body Mass Index on reference date

< 25

156

23

Referent

45

Referent

25 – 30

66

12

1.2 (0.5 – 2.5)

22

1.1 (0.5 – 2.4)

≥ 30

64

11

1.1 (0.6 – 2.0)

29

1.5 (0.8 – 2.6)

Number of live births

None

58

2

Referent

16

Referent

1

28

5

4.0 (0.7 – 22.3)

17

2.1 (0.9 – 4.9)

≥ 2

200

39

4.3 (1.0 – 18.8)

64

1.1 (0.6 – 2.2)


*PR, progesterone receptor; OC, oral contraceptive; HRT, hormone replacement therapy

† Odds ratio (OR) and 95% confidence intervals (CI) estimated from multivariable polytomous logistic regression including continuous age and three categories of education (high school or less, some college or trade school, and college graduate or graduate school) as confounding variables. None of the tests for linear trend was significant.

Custer et al. BMC Cancer 2006 6:152   doi:10.1186/1471-2407-6-152

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