|
Odds ratios for all glioma cases versus controls by quartiles of daily nutrient intake adjusted for age, gender, ethnicity, SES*, total calories**, and supplement use; San Francisco Bay Area Adult Glioma Study, 1991–2000.† |
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| Nutrient Quartile2 |
Combined Series I & II1 |
Series I (1991–1995) |
Series II (1996–2000) |
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|
|
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| OR |
95% CI3 |
p4 |
OR |
95% CI3 |
p4 |
OR |
95% CI3 |
p4 |
||||
|
|
||||||||||||
| Antioxidant Index |
||||||||||||
| 1st |
1 |
-- |
-- |
0.002 |
1 |
-- |
-- |
0.004 |
1 |
-- |
-- |
0.12 |
| 2nd |
0.81 |
0.61 |
1.07 |
0.82 |
0.56 |
1.20 |
0.79 |
0.53 |
1.20 |
|||
| 3rd |
0.82 |
0.62 |
1.09 |
0.77 |
0.52 |
1.14 |
0.89 |
0.59 |
1.35 |
|||
| 4th |
0.57 |
0.42 |
0.78 |
0.52 |
0.33 |
0.79 |
0.64 |
0.40 |
1.03 |
|||
| Vitamin E |
||||||||||||
| 1st |
1 |
-- |
-- |
0.45 |
1 |
-- |
-- |
0.46 |
1 |
-- |
-- |
0.06 |
| 2nd |
0.95 |
0.71 |
1.27 |
1.12 |
0.74 |
1.69 |
0.80 |
0.53 |
1.22 |
|||
| 3rd |
0.79 |
0.57 |
1.10 |
1.02 |
0.64 |
1.62 |
0.60 |
0.37 |
0.96 |
|||
| 4th |
0.91 |
0.62 |
1.34 |
1.28 |
0.75 |
2.19 |
0.62 |
0.35 |
1.09 |
|||
| Vitamin C |
||||||||||||
| 1st |
1 |
-- |
-- |
0.02 |
1 |
-- |
-- |
0.03 |
1 |
-- |
-- |
0.31 |
| 2nd |
0.74 |
0.56 |
0.97 |
0.75 |
0.51 |
1.09 |
0.72 |
0.48 |
1.09 |
|||
| 3rd |
0.73 |
0.55 |
0.97 |
0.71 |
0.48 |
1.05 |
0.75 |
0.49 |
1.14 |
|||
| 4th |
0.70 |
0.51 |
0.94 |
0.63 |
0.41 |
0.95 |
0.78 |
0.50 |
1.23 |
|||
| Carotenoids5 |
||||||||||||
| 1st |
1 |
-- |
-- |
0.02 |
1 |
-- |
-- |
0.23 |
1 |
-- |
-- |
0.03 |
| 2nd |
0.72 |
0.54 |
0.95 |
0.73 |
0.49 |
1.08 |
0.71 |
0.48 |
1.06 |
|||
| 3rd |
0.84 |
0.63 |
1.11 |
0.93 |
0.64 |
1.37 |
0.74 |
0.49 |
1.11 |
|||
| 4th |
0.65 |
0.48 |
0.88 |
0.70 |
0.46 |
1.06 |
0.60 |
0.39 |
0.93 |
|||
| α-Carotene |
||||||||||||
| 1st |
1 |
-- |
-- |
0.07 |
1 |
-- |
-- |
0.46 |
1 |
-- |
-- |
0.07 |
| 2nd |
0.87 |
0.66 |
1.15 |
1.03 |
0.70 |
1.52 |
0.73 |
0.49 |
1.09 |
|||
| 3rd |
0.83 |
0.63 |
1.10 |
1.06 |
0.72 |
1.58 |
0.64 |
0.42 |
0.96 |
|||
| 4th |
0.76 |
0.57 |
1.02 |
0.83 |
0.55 |
1.27 |
0.71 |
0.47 |
1.08 |
|||
| β-Carotene |
||||||||||||
| 1st |
1 |
-- |
-- |
0.04 |
1 |
-- |
-- |
0.24 |
1 |
-- |
-- |
0.09 |
| 2nd |
0.79 |
0.60 |
1.04 |
0.73 |
0.49 |
1.08 |
0.85 |
0.58 |
1.27 |
|||
| 3rd |
0.79 |
0.59 |
1.05 |
0.86 |
0.58 |
1.27 |
0.70 |
0.46 |
1.06 |
|||
| 4th |
0.72 |
0.54 |
0.98 |
0.73 |
0.48 |
1.10 |
0.72 |
0.47 |
1.11 |
|||
| Lutein |
||||||||||||
| 1st |
1 |
-- |
-- |
0.06 |
1 |
-- |
-- |
0.05 |
1 |
-- |
-- |
0.55 |
| 2nd |
1.02 |
0.78 |
1.34 |
1.17 |
0.81 |
1.70 |
0.86 |
0.57 |
1.29 |
|||
| 3rd |
0.86 |
0.65 |
1.14 |
0.88 |
0.60 |
1.30 |
0.85 |
0.56 |
1.28 |
|||
| 4th |
0.79 |
0.59 |
1.05 |
0.71 |
0.47 |
1.07 |
0.88 |
0.58 |
1.33 |
|||
| Lycopene |
||||||||||||
| 1st |
1 |
-- |
-- |
0.75 |
1 |
-- |
-- |
0.98 |
1 |
-- |
-- |
0.69 |
| 2nd |
0.91 |
0.69 |
1.21 |
0.99 |
0.67 |
1.46 |
0.83 |
0.55 |
1.25 |
|||
| 3rd |
1.01 |
0.76 |
1.33 |
1.05 |
0.72 |
1.55 |
0.96 |
0.63 |
1.45 |
|||
| 4th |
1.02 |
0.76 |
1.36 |
0.98 |
0.66 |
1.48 |
1.05 |
0.68 |
1.60 |
|||
| Cryptoxanthin |
||||||||||||
| 1st |
1 |
-- |
-- |
0.08 |
1 |
-- |
-- |
0.12 |
1 |
-- |
-- |
0.39 |
| 2nd |
0.96 |
0.73 |
1.26 |
0.76 |
0.52 |
1.11 |
1.26 |
0.84 |
1.88 |
|||
| 3rd |
0.92 |
0.69 |
1.21 |
0.86 |
0.59 |
1.26 |
1.00 |
0.65 |
1.52 |
|||
| 4th |
0.77 |
0.57 |
1.03 |
0.69 |
0.46 |
1.02 |
0.88 |
0.56 |
1.38 |
|||
| Genistein |
||||||||||||
| 1st |
1 |
-- |
-- |
0.06 |
1 |
-- |
-- |
0.20 |
1 |
-- |
-- |
0.11 |
| 2nd |
0.77 |
0.58 |
1.02 |
0.65 |
0.43 |
0.97 |
0.90 |
0.60 |
1.35 |
|||
| 3rd |
0.71 |
0.52 |
0.96 |
0.56 |
0.36 |
0.87 |
0.89 |
0.58 |
1.36 |
|||
| 4th |
0.74 |
0.54 |
1.02 |
0.74 |
0.45 |
1.20 |
0.68 |
0.44 |
1.06 |
|||
| Daidzein |
||||||||||||
| 1st |
1 |
-- |
-- |
0.003 |
1 |
-- |
-- |
0.30 |
1 |
-- |
-- |
0.0006 |
| 2nd |
0.77 |
0.58 |
1.01 |
0.96 |
0.65 |
1.41 |
0.60 |
0.40 |
0.90 |
|||
| 3rd |
0.61 |
0.46 |
0.82 |
0.65 |
0.43 |
0.98 |
0.56 |
0.37 |
0.86 |
|||
| 4th |
0.67 |
0.50 |
0.90 |
0.90 |
0.59 |
1.38 |
0.47 |
0.30 |
0.72 |
|||
| Biochanin A |
||||||||||||
| 1st |
1 |
-- |
-- |
0.10 |
1 |
-- |
-- |
0.04 |
1 |
-- |
-- |
0.84 |
| 2nd |
0.84 |
0.63 |
1.11 |
0.64 |
0.43 |
0.95 |
1.12 |
0.75 |
1.68 |
|||
| 3rd |
0.77 |
0.58 |
1.02 |
0.71 |
0.48 |
1.05 |
0.82 |
0.54 |
1.26 |
|||
| 4th |
0.79 |
0.59 |
1.07 |
0.61 |
0.40 |
0.92 |
1.06 |
0.69 |
1.65 |
|||
| Formononetin |
||||||||||||
| 1st |
1 |
-- |
-- |
0.58 |
1 |
-- |
-- |
0.58 |
1 |
-- |
-- |
0.81 |
| 2nd |
0.76 |
0.57 |
1.00 |
0.73 |
0.50 |
1.08 |
0.78 |
0.52 |
1.18 |
|||
| 3rd |
0.69 |
0.52 |
0.92 |
0.63 |
0.42 |
0.93 |
0.77 |
0.51 |
1.17 |
|||
| 4th |
0.95 |
0.72 |
1.27 |
0.94 |
0.64 |
1.39 |
0.96 |
0.63 |
1.47 |
|||
| Matairesinol |
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| 1st |
1 |
-- |
-- |
0.03 |
1 |
-- |
-- |
0.01 |
1 |
-- |
-- |
0.60 |
| 2nd |
0.74 |
0.56 |
0.98 |
0.59 |
0.40 |
0.86 |
0.95 |
0.64 |
1.42 |
|||
| 3rd |
0.80 |
0.60 |
1.06 |
0.78 |
0.54 |
1.15 |
0.80 |
0.53 |
1.22 |
|||
| 4th |
0.68 |
0.50 |
0.92 |
0.50 |
0.33 |
0.77 |
0.93 |
0.60 |
1.46 |
|||
| Secoisolarici-resinol |
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| 1st |
1 |
-- |
-- |
0.001 |
1 |
-- |
-- |
0.03 |
1 |
-- |
-- |
0.003 |
| 2nd |
1.01 |
0.77 |
1.33 |
0.74 |
0.50 |
1.08 |
1.37 |
0.93 |
2.03 |
|||
| 3rd |
0.81 |
0.61 |
1.08 |
0.80 |
0.55 |
1.17 |
0.80 |
0.52 |
1.23 |
|||
| 4th |
0.60 |
0.44 |
0.82 |
0.60 |
0.40 |
0.92 |
0.57 |
0.35 |
0.91 |
|||
| Coumestrol |
||||||||||||
| 1st |
1 |
-- |
-- |
0.001 |
1 |
-- |
-- |
0.01 |
1 |
-- |
-- |
0.02 |
| 2nd |
0.71 |
0.54 |
0.94 |
0.73 |
0.49 |
1.07 |
0.68 |
0.45 |
1.01 |
|||
| 3rd |
0.62 |
0.46 |
0.83 |
0.60 |
0.40 |
0.90 |
0.62 |
0.41 |
0.94 |
|||
| 4th |
0.59 |
0.43 |
0.80 |
0.57 |
0.37 |
0.88 |
0.59 |
0.37 |
0.93 |
|||
|
*Categories for socio-economic status (SES) combine highest education attained and/or household income range. **Total calories = ln(total calories). †Case-control distributions (= N) for quartiles of nutrient consumption are provided in supplemental table 1 [see 1]. 1Also adjusted for study series. 2Quartile cutpoints were calculated from series- and gender-specific nutrient intake distributions among controls. 3CI = Confidence interval. 4 p-value for chi-square test for trend. 5 alpha- and beta-Carotene. Note: Boxed values are statistically significant odds ratios (with corresponding 95% confidence intervals that exclude 1.00) or tests for trend. | ||||||||||||
Tedeschi-Blok et al. BMC Cancer 2006 6:148 doi:10.1186/1471-2407-6-148 |
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