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Characteristics and univariate comparisons of urine 1-hydroxypyrene glucuronide (1-OHPG) concentration in 199 healthy subjects from Rio Grande de Sul |
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| Characteristic |
Category N (%) |
1-OHPG (pmol/ml) median (IQR) |
P-value [1] |
|
|
|
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| Age quartile 1 |
<= 35 |
52 (26%) |
1.90 (0.23–3.55) |
0.027 |
| Age quartile 2 |
>35 |
49 (25%) |
1.90 (0.76–5.58) |
|
| Age quartile 3 |
>45 |
52 (26%) |
3.65 (1.36–7.58) |
|
| Age quartile 4 |
>58 |
46 (23%) |
1.55 (0.22–5.01) |
|
| Sex, N (%) |
Males |
98 (49%) |
2.19 (1.02–4.95) |
0.52 |
| Females |
101 (51%) |
2.03 (0.06–7.23) |
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| Residence, N (%) |
Rural |
35 (18%) |
1.97 (0.76–7.49) |
0.91 |
| Urban |
160 (82%) |
2.16 (0.48–5.30) |
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| Ever drink maté, N (%) |
No |
45 (23%) |
1.02 (0.05–2.03) |
0.0004 |
| Yes |
154 (77%) |
2.70 (0.89–6.92) |
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| Maté quartile 1 |
<100 mls/day |
53 (27%) |
1.01 (0.05–2.16) |
0.0001 |
| Maté quartile 2 |
>100 mls/day |
66 (33%) |
1.97 (0.33–5.58) |
|
| Maté quartile 3 |
>500 mls/day |
38 (19%) |
3.24 (1.40–8.15) |
|
| Maté quartile 4 |
>1000 mls/day |
42 (21%) |
4.06 (1.21–8.50) |
|
| Current tobacco smoker, N (%) |
No |
103 (52%) |
1.14 (0.05–3.17) |
<0.0001 |
| Yes |
96 (48%) |
3.76 (1.52–8.57) |
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| Ever regular tobacco smoker, N (%) |
No |
71 (36%) |
1.14 (0.05–2.35) |
<0.0001 |
| Yes |
128 (64%) |
3.41 (1.09–7.88) |
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| Urine cotinine, N (%) |
0 (<1–10 ng/mL) |
49 (25%) |
0.89 (0.05–2.35) |
<0.0001 |
| 1 (10–30) |
41 (21%) |
1.52 (0.05–4.00) |
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| 2,3,4 (30–500) |
39 (20%) |
1.40 (0.29–3.68) |
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| 5 (500–2000) |
36 (18%) |
4.89 (1.74–8.69) |
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| 6 (>2000) |
34 (17%) |
7.36 (2.66–7.36) |
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| Smoke Exposure2 |
No |
85 (43%) |
1.14 (0.051–3.17) |
<0.0001 |
| Yes |
114 (57%) |
3.30 (1.40–8.15) |
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| Ever prepare BBQ, N (%) |
No |
107 (54%) |
2.03 (0.08–5.58) |
0.31 |
| Yes |
92 (46%) |
2.136 (0.92–6.22) |
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| Prepared BBQ in the last week, N (%) |
No |
148 (74%) |
2.09 (0.31–5.60) |
0.63 |
| Yes |
51 (26%) |
2.09 (0.76–6.60) |
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| Prepare BBQ at least once a week, N (%) |
No |
145 (73%) |
2.22 (0.33–5.84) |
0.88 |
| Yes |
54 (27%) |
1.94 (0.95–5.90) |
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| Ever eat BBQ well done, N (%) |
No |
56 (28%) |
2.09 (0.24–7.52) |
0.82 |
| Yes |
143 (72%) |
2.09 (0.57–5.58) |
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| Ever drink beer, N (%) |
No |
126 (63%) |
2.44 (0.30–6.92) |
0.92 |
| Yes |
73 (37%) |
2.03 (1.02–4.63) |
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| Ever drink wine, N (%) |
No |
168 (84%) |
2.22 (0.05–6.66) |
0.62 |
| Yes |
31 (16%) |
1.97 (1.27–3.30) |
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| Ever drink cachaca, N (%) |
No |
165 (83%) |
1.97 (0.33–5.39) |
0.03 |
| Yes |
34 (17%) |
3.46 (1.52–8.19) |
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[1] All P-values come from the Wilcoxon rank sum test and the two-sided normal approximation P, except cotinine and mate quartile p-values which came from the Kruskal-Wallis test. [2] We defined smoke exposed subjects as subjects who are current tobacco smokers or have a cotinine value greater than category 1 (> 30 ng/mL). | ||||
Fagundes et al. BMC Cancer 2006 6:139 doi:10.1186/1471-2407-6-139 |
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