Table 3 |
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|
Stratified analysis on association between the TS3'-UTR del6 polymorphism and risk of breast cancer |
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|
Variables |
n (cases/controls) |
TS3'-UTR del6 |
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|
|
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|
n (cases/controls) |
aAdjusted OR (95% CI) |
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|
|
|
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|
del6/del6 |
del6/ins6 |
ins6/ins6 |
del6/del6 |
del6/ins6 |
ins6/ins6 |
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|
|
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|
Age |
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|
≤ 48 |
158/195 |
80/98 |
69/76 |
9/21 |
1.00 |
1.11(0.70–1.76) |
0.65(0.27–1.56) |
|
> 48 |
274/278 |
114/118 |
139/125 |
21/35 |
1.00 |
1.08(0.74–1.58) |
0.53(0.28–1.00) |
|
Menopausal status |
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|
Premenopausal |
197/210 |
93/105 |
90/82 |
14/23 |
1.00 |
1.22(0.80–1.86) |
0.75(0.36–1.56) |
|
Postmenopausal |
235/263 |
101/111 |
118/119 |
16/33 |
1.00 |
1.01(0.68–1.50) |
0.45(0.22–0.90) |
|
Age at menarche |
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|
<16 |
239/152 |
103/70 |
117/69 |
19/13 |
1.00 |
1.06(0.68–1.64) |
0.87(0.39–1.91) |
|
≥16 |
193/321 |
91/146 |
91/132 |
11/43 |
1.00 |
1.13(0.77–1.65) |
0.39(0.19–0.81) |
|
bAge at first live birth |
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|
≤ 25 |
166/226 |
70/91 |
85/104 |
11/31 |
1.00 |
1.04(0.67–1.61) |
0.47(0.22–1.03) |
|
>25 |
253/234 |
116/118 |
120/95 |
17/21 |
1.00 |
1.24(0.82–1.87) |
0.95(0.45–2.03) |
|
Family history of cancer |
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|
No |
319/378 |
143/173 |
155/165 |
21/40 |
1.00 |
1.07(0.77–1.48) |
0.63(0.35–1.13) |
|
Yes |
113/95 |
51/43 |
53/36 |
9/16 |
1.00 |
1.27(0.69–2.35) |
0.45(0.17–1.21) |
|
|
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|
aAdjusted for the other covariates presented in this table in a logistic regression model for each stratum. b Age at first live birth information was available in 460 controls and 419 breast cancer cases. |
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|
Zhai et al. BMC Cancer 2006 6:138 doi:10.1186/1471-2407-6-138 |
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