Table 3

Growth progression of IST-Mes3/2P cell line after orthotopic implantation in nude mice.

Days after implantation
54
61
68
75
82
89

Mediastinum nodules
< 101
<102
<103
<103
10–203
10–203
Pericardium nodules
< 101
<102
<103
<103
10–203
10–203
Parietal Pleura nodules
< 101
<102
<103
<103
10–203
10–203
Lungs nodules

-
-
-
<102
<102
Diaphragms nodules
-
-
-
-
<102
<102

2 × 106 IST-Mes3/2P cells were injected into the pleural cavity of nude mice. At indicated times mice were sacrificed and tumor nodules were counted, measured, removed and frozen for immunohistochemical analysis. Data shown are mean of 5 mice.

1 Nodule diameter ≤ 1 mm; 2 Nodule diameter = 2–3 mm; 3 Nodule diameter ≥ 3. No nodules were found before the days indicated in the table.

Martarelli et al. BMC Cancer 2006 6:130   doi:10.1186/1471-2407-6-130