Table 4

Toxicity-related treatment modifications

Treatment modifications
No. of patients
%

Any dose reduction
18
42.8%
Any cycle delay
20
47.6%
Toxicity-related withdrawals
3
7.1%

Time to treatment modification
Months
Range

Median time to reduction
2.0
1.0–5.3
Median time to first delay
1.3
0.5–3
Median time to toxicity-related withdrawal
3.9
1.8–6.0

Santini et al. BMC Cancer 2006 6:125   doi:10.1186/1471-2407-6-125