Calcitonin-producing well-differentiated neuroendocrine carcinoma (carcinoid tumor) of the urinary bladder: case report

doi:10.1186/1471-2407-5-88

BMC Cancer

Volume 5

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Mascolo M
Altieri V
Mignogna C
Napodano G
De Rosa G
Insabato L

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Altieri V
Mignogna C
Napodano G
De Rosa G
Insabato L
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Case report

Calcitonin-producing well-differentiated neuroendocrine carcinoma (carcinoid tumor) of the urinary bladder: case report

Massimo Mascolo¹ , Vincenzo Altieri² , Chiara Mignogna¹ , Giorgio Napodano² , Gaetano De Rosa¹ and Luigi Insabato¹

¹Department of Biomorphological and Functional Sciences, Pathology Section, University of Naples "Federico II", via S. Pansini 5, 80131, Naples, Italy

²Department of Urology, University of Naples "Federico II", via S. Pansini 5, 80131, Naples, Italy

author email corresponding author email

BMC Cancer 2005, 5:88doi:10.1186/1471-2407-5-88


Published:	27 July 2005

Abstract

Background

The occurrence of calcitonin-secreting primary carcinoid tumor of the urinary bladder is extremely rare.

Case presentation

The case of a 68-year-old male with carcinoid tumor arising in the urinary bladder is presented. Transurethral resection of a polypoid small tumor 0.4 cm in diameter was performed. Immunohistochemical study using neuroendocrine markers allowed a straightforward diagnosis of a low-grade neuroendocrine carcinoma (carcinoid tumor) of the urinary bladder. Immunohistochemistry demonstrated calcitonin immunoreactivity in the most of the tumor cells.

Conclusion

This tumor shows specific clinical, macroscopical and histological features and must be considered in the differential diagnosis of bladder neoplasms.