Table 1 |
||||
|
Comparison of tumor kinetics for four different MMR genotypes. The '+' and '-' symbols show the direction of change for each comparison. In each comparison, the genotype with the higher mutation rate had a lower acceleration and median age of onset. |
||||
|
Comparison |
Type |
Acceleration |
Age |
Mutation |
|
|
||||
|
Mlh3 v Mlh3Pms2 |
GI tumor |
+ |
+ |
- |
|
Mlh3 v Mlh1 |
GI tumor |
+ |
+ |
- |
|
Mlh3 v Mlh3Pms2 |
Lymphoma |
+ |
+ |
- |
|
Mlh3 v Mlh1 |
Lymphoma |
+ |
+ |
- |
|
Pms2 v Mlh3Pms2 |
Lymphoma |
+ |
+ |
- |
|
Pms2 v Mlh1 |
Lymphoma |
+ |
+ |
- |
|
Mlh3 v Pms2 |
Lymphoma |
+ |
+ |
- |
|
|
||||
|
Frank et al. BMC Cancer 2005 5:163 doi:10.1186/1471-2407-5-163 |
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