Table 4

Clinico-pathologic and immunohistochemical parameters in relation to Mcm2 immunoreactivity


Mcm2 immunoreactivity


Variable
 Categorisation
 n analysable
 negative (<40%)
 positive (≥40%)
 pa
Clinico-pathologic data:
Age at diagnosis

<65 years
 47
 27
 20
 1.000

≥65 years
 63
 37
 26
Gender

male
 72
 39
 33
 0.593

female
 57
 34
 23
Ann Arbor Stage

1
 15
 10
 5
 0.342

2
 34
 15
 19

3
 23
 14
 9

4
 35
 22
 13
International prognostic index

0
 2
 2
 0
 0.122

1
 48
 27
 21

2
 21
 14
 7

3
 20
 13
 7

4
 14
 4
 10
Bone marrow involvement

no
 72
 39
 33
 0.414

yes
 35
 22
 13
Extranodal involvement

no
 40
 27
 13
 0.103

yes
 62
 31
 31
Bulky disease

no
 62
 44
 20
 0.003

yes
 35
 13
 22
Serum levels of LDH at diagnosis

<300 U/l
 42
 23
 19
 0.505

≥300 U/l
 41
 26
 15

a two-sided Fisher's exact test; bold type representing significant data.

Obermann et al. BMC Cancer 2005 5:162   doi:10.1186/1471-2407-5-162