Table 2

Therapy results


Study Group
Total




70 to 75 years
> 75 years






80 mg/m2 (n = 15)
90 mg/m2 (n = 14)
60 mg/m2 (n = 7)
70 mg/m2 (n = 8)
(n = 44)

Treatment administered





     Chemotherapy cycles





          No.
46
42
14
23
125
          Median (range)
2 (1 to 4)
2 (1 to 5)
3 (1 to 5)
3 (1 to 6)
3 (1 to 6)
     Vinorelbine (median, mg/m2/wk)
8.6
8.8
9.4
10.3
8.9
     Cisplatin (median, mg/m2/wk)
13.6
15.9
11.2
14.4
14.5
Efficacy





     Complete response
-
-
-
1
1
     Partial response
8
8
2
3
21
     Stable disease
4
4
3
2
13
     Progressive disease
2
1
-
-
3
     Not evaluated
1
1
2
2
6
     Overall response rate (%)
53
57
29
50
50
Time to progression (median, in weeks)
25.0
23.0
15.7
18.4
27.0
Overall Survival





     Median (weeks)
31.0
17.3
26.6
31.7
30.1
     1-year (%)
40.0
35.7
28.5
37.5
36.3

Pereira et al. BMC Cancer 2004 4:69   doi:10.1186/1471-2407-4-69