Gene expression levels of progesterone metabolizing enzymes in paired (tumor versus normal) human breast biopsies. Expression level of each gene (in relation to 18S rRNA) was calculated as a tumor/normal ratio for each patient. Each bar and line represents the mean ± SEM of 11 paired tissue samples. * indicates significantly different from 5αR1 at p < 0.01 and from 5αR2 at p < 0.05 (by ANOVA and Student-Newman-Keuls test).
Lewis et al. BMC Cancer 2004 4:27 doi:10.1186/1471-2407-4-27