Figure 3.

Pgp expression in KB-V1 cells cultured in DMSO (vehicle control; lane 1), laboratory made-crude curcuminoids (lane 2), pure curcumin (lane 3), demethoxycurcumin (lane 4) and bisdemethoxycurcumin (lane 5) at 5 μM for 3 days The Pgp protein level was determined by Western blotting using Mab F4 (top), and quantified by laser densitometry (bottom). Data are means ± SEM of three independent experiments. Key: (*) significantly different from the vehicle control (P < 0.05).