Kaplan-Meier estimates of locoregional control in patients with head and neck cancer. Tumors treated with radiotherapy alone (solid lines) were either mutated (RT, LOH) or unmutated (RT, non LOH) at the M6P/IGF2R locus. Tumors treated with combined modality therapy (dashed lines) were also either mutated (CM, LOH) or unmutated (CM, non LOH) at the M6P/IGF2R locus. Patient number (n), patients that failed (parentheses), censored patients (angled bars), and median follow-up times are provided for each patient group. RT, radiotherapy; CM, combined modality therapy; LOH, loss of heterozygosity.
Jamieson et al. BMC Cancer 2003 3:4 doi:10.1186/1471-2407-3-4