Patient-specific variation in renal gene expression. Hybridization intensities are slightly more similar between a tumor and the tissue adjacent to that tumor than they are to tissue adjacent to the tumors of other patients. The frequency (y-axis) of varying degrees of differential expression (x-axis) when comparing the hybridization intensity for every tumor-sample probeset with the corresponding measurement in adjacent tissue is shown with the thin line. The frequency of varying degrees of differential expression observed when comparing the same tumor hybridization intensities with the corresponding measurements from tissues adjacent to the tumors of other patients is shown with the thick line.
Lenburg et al. BMC Cancer 2003 3:31 doi:10.1186/1471-2407-3-31