Table 3

Frequency distribution of all drug-related adverse events of at least grade 3
Dose level
Event 1 2 3 Total
Number of patients 4 (100%) 13 (100%) 7 (100%) 24 (100%)
Nausea 1 (25%) 2 (15%) 3 (43%) 6 (25%)
Vomiting 2 (50%) 2 (15%) 1 (14%) 5 (21%)
Dehydration 1 (14%) 1 (4%)
Diarrhoea 1 (14%) 1 (4%)
Dysphagia 1 (8%) 1 (4%)
Heartburn/dyspepsia 1 (14%) 1 (4%)
Fatigue 1 (25%) 1 (8%) 3 (43%) 5 (21%)
Pain 1 (14%) 1 (4%)
Platelets 1 (8%) 1 (14%) 2 (8%)
Leukocytes 1 (14%) 1 (4%)
Neutrophils 1 (14%) 1 (4%)

Moehler et al.

Moehler et al. BMC Cancer 2013 13:75   doi:10.1186/1471-2407-13-75

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