Figure 4.

Lovastatin-induced cell cycle arrest in G1. (A): Capan-2 spheroids treated or not with 10 μM lovastatin for 48 h. Visualization of Fucci-red and Fucci-green expressing cells. Nuclei are stained with DAPI (blue). Scale bar: 50 μm. (B) Capan-2 spheroids treated or not with 10 μM lovastatin for 24 or 48 h. Quantification of the percentage of Fucci-red and Fucci-green expressing cells as a function of the distance to the spheroid surface.

Laurent et al. BMC Cancer 2013 13:73   doi:10.1186/1471-2407-13-73
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