Open Access Research article

Prognostic value of α-fetoprotein and des-γ-carboxy prothrombin responses in patients with hepatocellular carcinoma treated with transarterial chemoembolization

Yong Kang Lee1†, Seung Up Kim1,3,4†, Do Young Kim1,3,4, Sang Hoon Ahn1,3,4,5, Kwang Hun Lee2,3,4, Do Yun Lee2,3,4, Kwang-Hyub Han1,3,4,5, Chae Yoon Chon1,3,4 and Jun Yong Park1,3,4*

  • * Corresponding author: Jun Yong Park DRPJY@yuhs.ac

  • † Equal contributors

1 Department of Internal Medicine, Yonsei University College of Medicine, 250 Seongsanno, Seodaemun–gu, Seoul 120-752, Korea

2 Department of Radiology, Yonsei University College of Medicine, Seoul, Korea

3 Liver Cancer Special Clinic, Yonsei University College of Medicine, Seoul, Korea

4 Liver Cirrhosis Clinical Research Center, Seoul, Korea

5 Brain Korea 21 Project for Medical Science, Seoul, Korea

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BMC Cancer 2013, 13:5 doi:10.1186/1471-2407-13-5

Published: 3 January 2013

Additional files

Additional file 1:

Table S1. Independent predictors between cTM responder with Radiologic non-responder ( n = 8 ) and cTM non-responder with radiologic responder ( n = 12 ). Figure S1. Progression-free survival (PFS) and overall survival (OS) curves of TM responder with radiologic non-responder and TM non-responder with radiologic non-responder. Both PFS and OS were not significantly different between TM responder with radiologic non-responder and TM non-responder with radiologic non-responder (5.1 vs. 5.1 months; log rank test, P=0.828 for PFS (A) and 33.8 vs. 7.5 months; log rank test, P=0.354 for OS (B)). Figure S2. Progression-free survival (PFS) and overall survival (OS) curves of cTM responder with radiologic responder and cTM non-responder with radiologic non-responder. PFS was similar between cTM responder with radiologic responder and cTM non-responder with radiologic non-responder (19.0 vs. 6.2 months; log rank test, P=0.065 for PFS (A)) whereas OS were significantly better in cTM responder with radiologic responder than cTM non-responder with radiologic non-responder (39.2 vs. 12.8 months; log rank test, P=0.031 for OS (B)).

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