Localization of M1 and M2 tumor-associated macrophages (TAMs) in tumors. (A) Tiled images from saline (untreated) MM. (B) Higher magnification of the surface of a saline (untreated) MM. (C) Interior of a saline (untreated) MM. (D) Tiled image of a MM treated with APMS-MB. (E) Higher magnification of the surface of APMS-MB-treated MM. (F) Interior of an APMS-MB-treated MM. Note that nuclei are stained blue, M1 TAMs are red, and M2 TAMs are green. White scale bars in A and D are 100 μM and in B, C, E and F are 50 μM.
Macura et al. BMC Cancer 2013 13:400 doi:10.1186/1471-2407-13-400