Table 2

Selected SNPs for genotyping
Gene SNP number SNP position Allele [major/minor] Function
OPG rs3102735 chr8: 119965070 T/C Transition substitution (5’ near region)
OPG rs2073618 chr8: 119964052 G/C Missense (p.K3N)
RANK rs1805034 chr18: 60027241 T/C Missense (p.V192A)
RANK rs35211496 chr18: 60021761 C/T Missense (p.H141Y)
RANKL rs9533156 chr13: 43147671 T/C Transition substitution (5’ near region)
RANKL rs2277438 chr13: 43155168 A/G Transition substitution (intron1/exon2 boundary)
RANKL rs1054016 chr13: 43182002 G/T Transversion substitution (3’ UTR)

RANK = receptor activator of nuclear factor-κB; RANKL = RANK ligand; SNP = single nucleotide polymorphism; OPG = osteoprotegerin.

Ney et al.

Ney et al. BMC Cancer 2013 13:40   doi:10.1186/1471-2407-13-40

Open Data