Open Access Research article

Genetic polymorphism of the OPG gene associated with breast cancer

Jasmin Teresa Ney16*, Ingolf Juhasz-Boess1, Frank Gruenhage2, Stefan Graeber3, Rainer Maria Bohle4, Michael Pfreundschuh5, Erich Franz Solomayer1 and Gunter Assmann5

Author Affiliations

1 Gynecology, Obstetrics and Reproductive Medicine, University Medical School of Saarland, 66421, Homburg/Saar, Saarland, Germany

2 Internal Medicine II, University Medical School of Saarland, 66421, Homburg/Saar, Saarland, Germany

3 Institute of Medical Biometry, Epidemiology and Medical Informatics, Saarland University, 66421, Homburg/Saar, Saarland, Germany

4 General and Surgical Pathology, University Medical School of Saarland, 66421, Homburg/Saar, Saarland, Germany

5 Internal Medicine I, José-Carreras-Center for Immuno- and Gene Therapy, University Medical School of Saarland, 66421, Homburg/Saar, Saarland, Germany

6 Universitätsklinikum des Saarlandes, Klinik für Frauenheilkunde, Geburtshilfe und Reproduktionsmedizin, Kirrbergerstr, 66421, Homburg/Saar, Germany

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BMC Cancer 2013, 13:40  doi:10.1186/1471-2407-13-40

Published: 31 January 2013

Additional files

Additional file 1:

Power analysis of the Χ2-tests for the allele frequency (2 x 2 contingency table, a, degree of freedom (DF) = 1) and the genotype distribution (2 x 3 contingency table, b, DF = 2) concerning the rs3102735 OPG SNP. Power was calculated by given effect size w, α (0.05) and total sample size (a: 1398; b: 699).

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