Complete responses of SA-1 tumor bearing mice after combined modality treatment. Single (panel A) and repetitive (panel B) intratumoral mIL-12 gene electrotransfer was used alone or combined with tumor irradiation. Abbreviations: mIL-12 = intratumoral injection of plasmid DNA coding for mIL-12; EGT mIL-12 = intratumoral mIL-12 gene electrotransfer; dsRed = intratumoral injection of non-therapeutic plasmid DNA; EGT dsRed = intratumoral dsRed gene electrotransfer; EP = electric pulse application on the tumors; IR = single dose radiation (10 Gy); All other groups = other therapeutic groups listed in Tables 1 and 2; 3× = triple therapy. Number of animals per treatment group is listed in Tables 1 and 2.
Sedlar et al. BMC Cancer 2013 13:38 doi:10.1186/1471-2407-13-38