Table 6

Characteristics of both combined models for diagnosis of EOC
Model L1 lasso penalty L2 ridge penalty
Blood expression values 5 genes 13 genes
Plasma protein values 5 proteins 6 proteins
AUCa (FIGO I-IV) 0.998 0.998
AUC (FIGO I-II) 0.976 0.979
Specificity (set) 99.6% 99.6%
Sensitivity 97.8% 95.6%
Classification error (bootstrap .632+) 3.1% 2.8%

aBootstrap .632+ validated area under the ROC curve.

Pils et al.

Pils et al. BMC Cancer 2013 13:178   doi:10.1186/1471-2407-13-178

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