Table 1 |
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|
Patient characteristics at time of diagnosis |
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|
Number (%) |
miRNA-126 expression level (μm2) |
||
|
(n = 89) |
Median (95% CI) |
p - value |
|
|
|
|||
|
Sex |
|||
|
|
|||
|
Male |
45 (51) |
2533 (1690-3285) |
0.84 |
|
|
|||
|
Female |
44 (49) |
2354 (1650-3163) |
|
|
|
|||
|
Age (years) |
|||
|
|
|||
|
Mean (SD) |
63.2 (8.2) |
||
|
|
|||
|
Range |
24 - 80 |
||
|
|
|||
|
> mean |
49 (55) |
2088 (1556-3223) |
0.56 |
|
|
|||
|
< mean |
40 (45) |
2531 (1896-3355) |
|
|
|
|||
|
ECOG Performance status |
|||
|
|
|||
|
0 |
37 (42) |
2041 (1551-3163) |
0.40 |
|
|
|||
|
1-2 |
52 (58) |
2535 (1708-3489) |
|
|
|
|||
|
Localization |
|||
|
|
|||
|
Rectum |
18 (20) |
3038 (1690-4030) |
0.37 |
|
|
|||
|
Colon |
71 (80) |
2141 (1650-2638) |
|
|
|
|||
|
Left colon |
47 (66) |
2141 (1589-2818) |
0.99 |
|
|
|||
|
Right colon |
24 (34) |
2232 (1452-3355) |
|
|
|
|||
|
MSI status* |
|||
|
|
|||
|
MSI |
8 (11) |
2193 (1374-5421) |
0.61 |
|
|
|||
|
MSS |
62 (89) |
2355 (1705-2818) |
|
|
|
|||
|
Metastatic sites* |
|||
|
|
|||
|
1 |
27 (31) |
3575 (3163-4521) |
< 0.0001 |
|
|
|||
|
≥ 2 |
59 (69) |
1857 (151-2376) |
|
|
|
|||
|
CI confidence interval, SD standard deviation, ECOG Eastern Cooperative Oncology Group, MSI microsatellite instability, MSS , microsatellite stable *MSI status was not assessed in all patients **A reliable estimate of the number of metastatic sites was not possible in 3 patients |
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|
Hansen et al. BMC Cancer 2012 12:83 doi:10.1186/1471-2407-12-83 |
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