High TOX3 mRNA was associated with shorter survival. Tumours were classified into high and low expressing tumours based on mRNA levels that were above or below average, respectively. Accordingly, survival was analysed in the whole group of patients: A) OS: 88 low vs. 46 high, log rank p = 0.022; B) DMFS: 83 low vs. 43 high, log rank p = 0.015 and in ER positive patients: C) OS: 53 low vs. 35 high, log rank p = 0.017; D) DMFS: 49 low vs. 33 high, log rank p = 0.029.
Gudmundsdottir et al. BMC Cancer 2012 12:621 doi:10.1186/1471-2407-12-621