Table 1

Genes up regulated in SK-NEP-1 cells treated with YM155 compared with DMSO control group
Gene Symbol +DMSO +YM155 Ratio P value
1 TNF Tumor necrosis factor 0.052 3.274 62.850 0.0085
2 FOXO1 Forkhead box O1 3.109 59.967 19.287 0.0091
3 IER3 Immediate early response 3 53.221 795.891 14.955 0.0093
4 PEA15 Phosphoprotein enriched in astrocytes 15 85.200 642.789 7.545 0.0105
5 CD5 CD5 molecule 0.079 0.584 7.405 0.0105
6 NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 127.186 919.431 7.229 0.0106
7 TNFAIP3 Tumor necrosis factor, alpha-induced protein 3 69.132 449.671 6.505 0.0109
8 NFKB1 nuclear factor of kappa gene enhancer in B-cells 1  58.200 377.771 6.491 0.0109
9 CRYAB Crystallin, alpha B 7.704 49.315 6.401 0.0109
10 DDIT3 DNA-damage-inducible transcript 3 134.710 768.681 5.706 0.0113
11 CRADD CASP2 domain containing adaptor with death domain 10.127 56.007 5.531 0.0114
12 BNIP1 BCL2/adenovirus E1B 19 kDa interacting protein 1 89.770 475.609 5.298 0.0115
13 BBC3 BCL2 binding component 3 1.388 6.896 4.969 0.0118
14 NOX5 NADPH oxidase, EF-hand calcium binding domain 5  0.213 1.057 4.953 0.0118
15 CASP7 Caspase 7, apoptosis-related cysteine peptidase 20.274 95.136 4.693 0.0120
16 PIM2 Pim-2 oncogene 29.093 118.888 4.087 0.0127
17 CEBPG CCAAT/enhancer binding protein (C/EBP), gamma 11.867 47.745 4.023 0.0128
18 EDA Ectodysplasin A 0.710 2.846 4.009 0.0128
19 SOCS2 Suppressor of cytokine signaling 2 0.258 1.018 3.953 0.0129
20 CDKN1A Cyclin-dependent kinase inhibitor 1A (p21, Cip1) 124.431 479.383 3.853 0.0131
21 IL1A Interleukin 1, alpha 146.968 423.629 2.882 0.0155
22 BIRC8 Baculoviral IAP repeat containing 8  0.248 0.692 2.785 0.0159
23 SERPINB2 Serpin peptidase inhibitor, clade B member 2 0.136 0.362 2.659 0.0165
24 CASP9 Caspase 9, apoptosis-related cysteine peptidase 330.442 853.550 2.583 0.0169
25 LTB Lymphotoxin beta (TNF superfamily, member 3) 0.052 0.134 2.580 0.0170
26 PMAIP1 Phorbol-12-myristate-13-acetate-induced protein 1  258.441 642.950 2.488 0.0175
27 NUPR1 Nuclear protein, transcriptional regulator, 1 25.295 61.632 2.437 0.0179
28 BIRC3 Baculoviral IAP repeat containing 3 97.141 232.642 2.395 0.0183
29 DIABLO IAP-binding mitochondrial protein  178.419 417.832 2.342 0.0187
30 LTBR Lymphotoxin beta receptor 120.546 280.744 2.329 0.0188
31 COL4A3 Collagen, type IV, alpha 3 5.993 12.916 2.155 0.0208
32 FOXO3 Forkhead box O3 34.671 71.488 2.062 0.0222

Tao et al.

Tao et al. BMC Cancer 2012 12:619   doi:10.1186/1471-2407-12-619

Open Data