Table 1

Primary information for 16 genotyped SNPs in oxidative pathway genes
Genotyped SNPs Location/or Amino acid change MAF for Chinese in databasea P value for HWE testb % Genotyping rate
GPX1: rs1800668 C>T Promoter 0.078 0.706 99.1
CAT: rs769214 G>A 5’region 0.293 0.275 97.9
CAT: rs7943316 A>T 5’region 0.256 0.822 98.0
PON1: rs854552 T>C 3' UTR 0.179 0.195 99.1
PON1: rs662 G>A nsSNP/Q192R 0.430 0.424 97.7
NQO1: rs10517 C>T 3' UTR 0.381 0.397 97.7
NQO1: rs1800566 T>C nsSNP/S1P 0.478 0.757 97.5
MnSOD: rs4880 T>C nsSNP/V16A 0.146 0.914 98.8
MnSOD: rs5746136 G>A 3' UTR 0.422 0.264 98.7
SOD3: rs2536512 G>A nsSNP/T58A 0.100 0.730 98.6
SOD3: rs2695232 C>T 3' UTR 0.367 0.284 98.6
NOS1: rs2682826 C>T 3' UTR 0.256 0.163 98.0
NOS1: rs1047735 T>C nsSNP/Q902H 0.488 0.522 98.4
NOS2: rs2297518 G>A nsSNP/L608S 0.175 0.426 97.2
NOS2: rs10459953 G>C Promoter 0.489 0.790 99.1
NOS3: rs1799983 G>T nsSNP/D298E 0.111 0.586 97.9

Abbreviations: MAF minor allele frequency, HWE Hardy-Weinberg equilibrium.

aMinor allele frequency in the Chinese (CHB, Han Chinese in Beijing, China) population, as reported in dbSNP database.

bP values were calculated from our control genotype.

Zhao et al.

Zhao et al. BMC Cancer 2012 12:617   doi:10.1186/1471-2407-12-617

Open Data