Table 4 |
|||||||
| Toxicity during and after salvage chemoradiotherapy | |||||||
| Toxicity | Grade 0 | Grade 1 | Grade 2 | Grade 3 | Grade 4 | Toxicity of any grade (%) | Toxicity of grade 3–4 (%) |
| Hematological toxicity | |||||||
| Leukopenia | 6 | 11 | 11 | 3 | 0 | 81 | 10 |
| Neutropenia | 12 | 13 | 5 | 1 | 0 | 61 | 3 |
| Anemia | 4 | 14 | 10 | 3 | 0 | 87 | 10 |
| Thrombocytopenia | 12 | 16 | 3 | 0 | 0 | 61 | 0 |
| AST/ALT | 20 | 9 | 2 | 0 | 0 | 35 | 0 |
| Non-hematological toxicity | |||||||
| Fatigue | 7 | 17 | 5 | 2 | 0 | 77 | 6 |
| Anorexia | 4 | 18 | 3 | 5 | 1 | 87 | 19 |
| Nausea | 9 | 15 | 5 | 2 | 0 | 71 | 6 |
| Vomiting | 24 | 6 | 0 | 1 | 0 | 23 | 3 |
| Diarrhea | 21 | 8 | 2 | 0 | 0 | 32 | 0 |
| Abdominal pain | 20 | 9 | 2 | 0 | 0 | 35 | 0 |
| Stomatitis | 29 | 2 | 0 | 0 | 0 | 6 | 0 |
| Skin rash | 29 | 2 | 0 | 0 | 0 | 6 | 0 |
| Infection | 29 | 0 | 1 | 1 | 0 | 6 | 3 |
| Gastrointestinal ulcer | 27 | 0 | 2 | 1 | 1 | 13 | 6 |
AST aspartate transaminase, ALT alanine transaminase.
Mayahara et al. BMC Cancer 2012 12:609 doi:10.1186/1471-2407-12-609