Table 5

Frequency of nausea and vomiting AEs during 1stcycle of chemotherapy
Frequency of nausea and vomiting AE (all grade) during 1stcycle of chemotherapy
Placebo n = 217 Cocculine®n = 214 All n = 431 p
Missing data 39 20 59
Number of patients evaluable 178 194 372
Number of patient with at least 1 AE nausea (%) 91 (51.1) 92 (47.4) 83 (49.2) 0.48
Missing data 39 20 59
Number of patients evaluable 178 194 372
Number of patient with at least 1 AE vomiting, n (%) 35 (19.7) 41 (21.1) 76 (20.4) 0.72
Frequency of severe nausea and vomiting AE (Grade ≥ 2) during 1stcycle of chemotherapy
Placebo n = 217 Cocculine n = 214 All n = 431 p
Missing data 47 29 76
Number of patients evaluable, n 170 185 355
Number of patient with at least 1 severe nausea AE (i.e. Grade ≥2), n (%) 30 (17.6) 29 (15.7) 59 (16.6) 0.62
Missing data 41 22 63
Number of patients evaluable 176 192 368
Number of patient with at least 1 severe vomiting AE (i.e. Grade ≥ 2), n (%) 19 (10.8) 23 (12.0) 42 (11.4) 0.72

†Person’s chi-square test.

Pérol et al.

Pérol et al. BMC Cancer 2012 12:603   doi:10.1186/1471-2407-12-603

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