Open Access Research article

Phosphorylation of p90RSK is associated with increased response to neoadjuvant chemotherapy in ER-positive breast cancer

Hyeong-Gon Moon1, Jae Kyo Yi1, Hee Sung Kim2, Hea Young Lee1, Kyung-Min Lee1, Minju Yi1, Sookyung Ahn1, Hee-Chul Shin3, Ji-hyun Ju4, Incheol Shin4, Wonshik Han1 and Dong-Young Noh1*

  • * Corresponding author: Dong-Young Noh dynoh@snu.ac.kr

  • † Equal contributors

Author Affiliations

1 Department of Surgery and Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea

2 Department of Pathology, Gachon University Gil Hospital, Gachon University of Medicine and Science, Incheon, Korea

3 Department of Surgery, Chung-Ang University College of Medicine, Seoul, Korea

4 Department of Life Science, College of Natural Science, Hanyang University, Seoul, Korea

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BMC Cancer 2012, 12:585  doi:10.1186/1471-2407-12-585

Published: 10 December 2012

Additional files

Additional file 1:

Figure S1. Scatter plot for the relationship between phosphor-p90RSK expression and chemotherapy sensitivity in 12 breast cancer cell lines. Cell survival denotes for the proportion of cancer cells surviving after doxorubicin 10uM treatment. Pearson correlation coefficient and p value were derived from correlation analysis.

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Additional file 2:

Table S1. Univariate and Multivariate analysis for factors affecting pCR.

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