Table 2

Averaged PLA2R1 methylations in DNA from blood of normal individuals (Control, N = 52) and leukemic patients (Leukemia, N = 32) analysed by MS-HRM
Group N Methylation (mean ± SD)
Control 52 6.9% ± 2.5%
Leukemia 32 28.9% ± 17.8% **

** p = <0.001 in comparison to controls

In the control group, one individual exhibited a PLA2R1 methylation of 21% and in the leukemic group, two patients had methylations of 7% and 3% (patient details see in Additional file 1: TableS1). The 95th percentile value usable as cut-off averaged 9%.

Menschikowski et al.

Menschikowski et al. BMC Cancer 2012 12:576   doi:10.1186/1471-2407-12-576

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