|Averaged PLA2R1 methylations in DNA from blood of normal individuals (Control, N = 52) and leukemic patients (Leukemia, N = 32) analysed by MS-HRM|
|Group||N||Methylation (mean ± SD)|
|Control||52||6.9% ± 2.5%|
|Leukemia||32||28.9% ± 17.8% **|
** p = <0.001 in comparison to controls
In the control group, one individual exhibited a PLA2R1 methylation of 21% and in the leukemic group, two patients had methylations of 7% and 3% (patient details see in Additional file 1: TableS1). The 95th percentile value usable as cut-off averaged 9%.
Menschikowski et al.
Menschikowski et al. BMC Cancer 2012 12:576 doi:10.1186/1471-2407-12-576