Table 3

Association between hepatocellular carcinoma and TLR2 and TLR9 SNPs

Gene

SNP

Genotype

Odds Ratio (95% CI)

P Value

Odds Ratio (95% CI) †

P Value


TLR2

rs7696323

C/C

1

1

C/T

1.014 (0.684 - 1.503)

0.946

1.001 (0.673 - 1.489)

0.995

T/T

0.555 (0.271 - 1.137)

0.108

0.560 (0.271 - 1.157)

0.118

rs1898830

A/A

1

1

A/G

0.866 (0.570 - 1.317)

0.502

0.902 (0.591 - 1.378)

0.634

G/G

1.536 (0.891 - 2.647)

0.122

1.531 (0.885 - 2.649)

0.128

rs11938228

C/C

1

1

A/C

0.848 (0.560 - 1.284)

0.437

0.884 (0.582 - 1.344)

0.565

A/A

1.354 (0.789 - 2.324)

0.272

1.340 (0.777 - 2.309)

0.292

rs3804099

T/T

1

1

C/T

0.502 (0.337 - 0.745)

0.001

0.493 (0.331 - 0.736)

0.001

C/C

1.047 (0.506 - 2.166)

0.902

1.048 (0.503 - 2.182)

0.901

rs3804100

T/T

1

1

C/T

0.520 (0.350 - 0.772)

0.001

0.509 (0.342 - 0.759)

0.001

C/C

1.087 (0.474 - 2.490)

0.844

0.844 (0.441 - 2.358)

0.964

TLR9

rs352140

C/C

1

1

C/T

0.829 (0.557 - 1.233)

0.354

0.861 (0.576 - 1.286)

0.464

T/T

1.518 (0.814 - 2.831)

0.19

1.438 (0.767 - 2.695)

0.258

rs352139

G/G

1

1

G/A

1.142 (0.768 - 1.698)

0.512

1.180 (0.790 - 1.761)

0.419

A/A

1.584 (0.835 - 3.004)

0.159

1.521 (0.798 - 2.900)

0.202


† Adjusted for age and sex. P value was calculated by a χ2-test 2 × 2 contingency table (df = 1)

Junjie et al. BMC Cancer 2012 12:57   doi:10.1186/1471-2407-12-57

Open Data