Snail expression in gastric adenocarcinoma (GC) tissue samples and Kaplan–Meir plots of overall survival of 314 GC patients. Snail was mostly expressed in nuclei of GC cells (intestinal type (A), and diffuse type (signet ring) cells (B)) included in tissue array specimens. Some reactive fibroblasts also showed Snail nuclear expression (magnification: ×400). C. Kaplan–Meier analysis of overall survival of GC patients based on Snail expression. A linear relationship between increased Snail nuclear expression and shorter survival was seen among GC patients (P = 0.023). Log-rank test was used to calculate P values.
Shin et al. BMC Cancer 2012 12:521 doi:10.1186/1471-2407-12-521