Table 1

SEREX-defined genes identified by autologous screening of C-164 cDNA library
Antigen No. of clones Identity/similarities DNA microarray (fold change)1
C-164 C-1 C-29
OY-CO-1 1 Lectin, galactoside-binding, soluble, 3 binding protein (LGALS3BP) 0.72 0.60 0.46
OY-CO-2 1 Rho GTPase-activating protein 18(ARHGAP18) 4.57 1.44 1.50
OY-CO-3 10 Dihydrolipoamide dehydrogenase (DLD) 1.27 0.55 0.30
OY-CO-4 1 Adenomatous polyposis coli (APC), transcript variant 3 3.61 0.74 3.22
OY-CO-5 1 MRE11 meiotic recombination 11 homolog A (MRE11A), transcript variant 1 2.66 9.02 3.72
OY-CO-6 1 Heat shock protein 90 kDa beta (Grp94), member 1 (HSP90B1) 1.02 2.75 1.25
OY-CO-7 1 Transcription elongation factor B (SII), polypeptide 2 (18 kDa, elongin B) (TCEB2), transcript variant 1 1.52 2.74 1.48
OY-CO-8 1 Wilms tumor 1-associated protein (WTAP), transcript variant 2 1.06 0.35 0.42
OY-CO-9 1 Ribosomal protein L35a (RPL35A) 1.77 1.95 2.31
OY-CO-10 1 Polyglutamine-binding protein 1 (PQBP1), transcript variant 7 1.26 1.27 1.30
OY-CO-11 2 PRP38 pre-mRNA processing factor 38 (yeast) domain containing B (PRPF38B), transcript variant 1 3.03 2.88 2.51
OY-CO-12 2 Coatomer protein complex, subunit alpha (COPA), transcript variant 2 1.26 0.73 0.75
OY-CO-13 1 Keratin 18 (KRT18), transcript variant 1 1.46 1.24 0.66
OY-CO-14 1 No strong homology, retrotransposon MSTP055 mRNA - - -
OY-CO-15 1 Ribosomal protein L13 (RPL13), transcript variant 2 0.92 0.84 1.67
OY-CO-16 1 Partial mRNA for KLEIP (kelch-like ECT2 interacting protein), (KLHLX gene) - - -
OY-CO-17 2 BTB (POZ) domain containing 2 (BTBD2) 0.79 0.84 0.83
OY-CO-18 1 Nuclear receptor interacting protein 1 (NRIP1) 0.81 0.87 0.92
OY-CO-19 1 Ribosomal protein L8 (RPL8), transcript variant 2 1.01 2.63 1.69
OY-CO-20 2 Glutamine-fructose-6-phosphate transaminase 1 (GFPT1) 2.92 1.00 0.59
OY-CO-21 1 WD repeat, sterile alpha motif and U-box domain containing 1 (WDSUB1), transcript variant 3 1.69 1.19 0.76

1Gene expressions in 3 colon cancer tissues were compared with normal colon tissues by cDNA microarray analysis.

Hanafusa et al.

Hanafusa et al. BMC Cancer 2012 12:520   doi:10.1186/1471-2407-12-520

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