Table 5

Second non-breast primary malignancies
Gene Mutation 2nd tumour Diagnosis relative to Breast Primary (years)
BRCA2 BRCA2 2988 del C (STOP 959) Ascending Colon - Adenocarcinoma 15.5
BRCA2 BRCA2 698_702 del AGTCA (STOP 180) Prostate - Acinar Adenocarcinoma 0.8
BRCA2 BRCA2 8168_8169 ins C (STOP 2661) Prostate - Acinar Adenocarcinoma 1.4
BRCA2 BRCA2 del exons 1_27 Parotid gland - Oxyphilic adenocarcinoma 6.2
BRCA2 BRCA2 IVS 7–1 G>A Lung - squamous cell carcinoma 13.8
BRCAX Adenocarcinoma - unknown primary 3.0
BRCAX Lung – Carcinoma not otherwise specified. 9.4
BRCAX Prostate - Acinar Adenocarcinoma 9.5
BRCAX Prostate - Acinar Adenocarcinoma 3.0 years prior to breast cancer
BRCAX Prostate - Acinar Adenocarcinoma 1.3 years prior to breast cancer

Deb et al.

Deb et al. BMC Cancer 2012 12:510   doi:10.1186/1471-2407-12-510

Open Data