|Selected details of the 22 studies of FEV1 and lung cancer|
|Study REF||Reference(s)||Location||Baseline population||Follow-up period (years)||Lung cancer cases||Newcastle-Ottawa scorea|
|BEATY||||USA, Baltimore||874 men aged 17+ entering study on aging between 1958 and 1979||24||15||7|
|CALABR||||Italy, multicentre||3804 male and female current or former smokers aged 50–75 entering study between 2000 and 2008||5||57||6|
|CARET||[25,26]||USA, multicentre||3033 male asbestos exposed heavy smokers aged 45–74 entering study between 1985 and 1994||20||205||8|
|CARTA||||Italy, Sardinia||696 male silicotics aged up to 74 entering study between 1964 and 1970||23||22||6|
|FINKEL||||Canada, Ontario||733 male radon exposed uranium miners studied in 1974||18||42||5|
|ISLAM||[4,38]||USA, Michigan||3956 men and women aged 25+ entering community health study between 1962 and 1965||25||77||9|
|LANGE||||Denmark, Copenhagen||13946 men and women aged 20+ entering heart health study between 1976 and 1978||12||225||8|
|MALDON||||USA, Minnesota||1520b male and female current or former smokers aged 50+ studied in 1999||4||64||5|
|MANNIN||||USA, national||5402 men and women aged 25–74 participating in NHANES between 1971 and 1975||22||113||9|
|MRFIT||[2,30]||USA, multicentre||6613 men aged 35–57 at high risk of heart disease participating in the Multiple Risk Factor Intervention Trial between 1973 and 1982||26||363||8|
|NOMURA||||USA, Hawaii||6317 Japanese-American men aged 46–68 entering study between 1965 and 1968||22||172||8|
|PETO||||UK, five areas||2718 men in occupational groups aged 25–64 entering study between 1954 and 1961||25||103||7|
|PURDUE||||Sweden, national||176997 male construction workers entering study between 1971 and 1993||31||834||7|
|RENFRE||[3,28]||Scotland, two cities||15244 men and women aged 45–64 entering study between 1972 and 1976||23||651||8|
|SKILLR||||USA, Minnesota||226c men and women aged 45–59 living in rural areas entering study between 1973 and 1974||11||11||7|
|SPEIZE||||USA six cities||8427 men and women aged 25–74 entering study between 1974 and 1977||12||61||8|
|STAVEM||||Norway, Oslo||1623 male workers in five companies aged 40–59 entering study between 1972 and 1975||26||42||7|
|TAMMEM||||Canada, British Columbia||2596 male and female current and former smokers of 20+ pack-years aged 40+ studied in 1990||17||154||8|
|TOCKMA||||USA, Baltimore||3728 male current smokers and recent quitters, smoking 1+ packs/day, aged 45+ studied in 1987||2d||19||7|
|VANDEN||||USA, California||153925 male and female members of the Kaiser Permanente Medical Care Program entering study between 1964 and 1972||24||1514||9|
|WILES||||South Africa, national||2062 male gold miners aged 45–54 entering study between 1968 and 1970||18||74||5|
|WILSON||||USA, Pennsylvania||1553 male and female current or former smokers of 10+ cigs/day for 25+ years with FEV1/FVC <0.7, aged 50–79, entering study from 2002||5||67||6|
a See Methods for a description of this score. The maximum possible value is 9.
b Nested case–control analysis involving 64 cases and 377 controls drawn from original population of 1520.
c Nested case–control analysis involving 113 men and women with FEV1 <70% predicted, and 113 with FEV1 of 85% or more drawn from a study with original sample size not stated.
d Although the mean follow-up was less than 3 years, follow-up for some subjects was 3 years or more, so the study was not considered to have failed the inclusion criteria.
Fry et al.
Fry et al. BMC Cancer 2012 12:498 doi:10.1186/1471-2407-12-498