Table 2

Selected details of the 22 studies of FEV1 and lung cancer
Study REF Reference(s) Location Baseline population Follow-up period (years) Lung cancer cases Newcastle-Ottawa scorea
BEATY [23] USA, Baltimore 874 men aged 17+ entering study on aging between 1958 and 1979 24 15 7
CALABR [1] Italy, multicentre 3804 male and female current or former smokers aged 50–75 entering study between 2000 and 2008 5 57 6
CARET [25,26] USA, multicentre 3033 male asbestos exposed heavy smokers aged 45–74 entering study between 1985 and 1994 20 205 8
CARTA [19] Italy, Sardinia 696 male silicotics aged up to 74 entering study between 1964 and 1970 23 22 6
FINKEL [27] Canada, Ontario 733 male radon exposed uranium miners studied in 1974 18 42 5
ISLAM [4,38] USA, Michigan 3956 men and women aged 25+ entering community health study between 1962 and 1965 25 77 9
LANGE [5] Denmark, Copenhagen 13946 men and women aged 20+ entering heart health study between 1976 and 1978 12 225 8
MALDON [31] USA, Minnesota 1520b male and female current or former smokers aged 50+ studied in 1999 4 64 5
MANNIN [32] USA, national 5402 men and women aged 25–74 participating in NHANES between 1971 and 1975 22 113 9
MRFIT [2,30] USA, multicentre 6613 men aged 35–57 at high risk of heart disease participating in the Multiple Risk Factor Intervention Trial between 1973 and 1982 26 363 8
NOMURA [7] USA, Hawaii 6317 Japanese-American men aged 46–68 entering study between 1965 and 1968 22 172 8
PETO [35] UK, five areas 2718 men in occupational groups aged 25–64 entering study between 1954 and 1961 25 103 7
PURDUE [37] Sweden, national 176997 male construction workers entering study between 1971 and 1993 31 834 7
RENFRE [3,28] Scotland, two cities 15244 men and women aged 45–64 entering study between 1972 and 1976 23 651 8
SKILLR [9] USA, Minnesota 226c men and women aged 45–59 living in rural areas entering study between 1973 and 1974 11 11 7
SPEIZE [20] USA six cities 8427 men and women aged 25–74 entering study between 1974 and 1977 12 61 8
STAVEM [21] Norway, Oslo 1623 male workers in five companies aged 40–59 entering study between 1972 and 1975 26 42 7
TAMMEM [39] Canada, British Columbia 2596 male and female current and former smokers of 20+ pack-years aged 40+ studied in 1990 17 154 8
TOCKMA [10] USA, Baltimore 3728 male current smokers and recent quitters, smoking 1+ packs/day, aged 45+ studied in 1987 2d 19 7
VANDEN [40] USA, California 153925 male and female members of the Kaiser Permanente Medical Care Program entering study between 1964 and 1972 24 1514 9
WILES [43] South Africa, national 2062 male gold miners aged 45–54 entering study between 1968 and 1970 18 74 5
WILSON [44] USA, Pennsylvania 1553 male and female current or former smokers of 10+ cigs/day for 25+ years with FEV1/FVC <0.7, aged 50–79, entering study from 2002 5 67 6

a See Methods for a description of this score. The maximum possible value is 9.

b Nested case–control analysis involving 64 cases and 377 controls drawn from original population of 1520.

c Nested case–control analysis involving 113 men and women with FEV1 <70% predicted, and 113 with FEV1 of 85% or more drawn from a study with original sample size not stated.

d Although the mean follow-up was less than 3 years, follow-up for some subjects was 3 years or more, so the study was not considered to have failed the inclusion criteria.

Fry et al.

Fry et al. BMC Cancer 2012 12:498   doi:10.1186/1471-2407-12-498

Open Data