Table 3

Actuarial overall survival according to potential factors and the result of univariate and multivariate analysis
No. metastases 1-year actuarial OS (%) Median OS (months) Univariatepvalue Multivariatepvalue
Gender 0.955
male 55 35 9.9
female 53 33 9.1
Age 0.777
< 57.5 years (median) 54 44 9.9
≥ 57.5 years (median) 54 24 6.3
NSCLC vs. Others 0.778
NSCLC 43 40 7.2
others 65 32 10.7
RPA 0.010
I 36 50 11.8
II 72 28 4.7
Extracerebral activity of primary tumor 0.001 0.001
not detectable 30 47 11.7
stable 25 48 10.0
progredient 53 23 4.0
Objective of therapy 0.217
primary 52 37 8.9
recurrence 56 34 10.0
Steroid uptake 0.005 0.030
yes 51 18 5.4
no 57 51 13.0
GTV 0.004 0.019
< 2 ccm 57 49 11.5
≥ 2 ccm 51 20 5.4
EQD2 (35 Gy) 0.021 0.298
≤ 35 Gy 24 13 3.6
> 35 Gy 84 42 10.7
EQD2 (median 39 Gy) 0.009 0.012
< 39 Gy 54 26 7.2
≥ 39 Gy 54 44 11.5
V4 Gy (median 16.7 ccm) 0.271
< 16.7 ccm 56 32 7.2
≥ 16.7 ccm 52 38 9.1
Time between diagnosis of primary and diagnosis of brain metastases 0.092
< 12.5 months 52 30 9.1
≥ 12.5 months 56 40 8.9

Märtens et al.

Märtens et al. BMC Cancer 2012 12:497   doi:10.1186/1471-2407-12-497

Open Data