Open Access Highly Accessed Case report

First case of isolated vaginal metastasis from breast cancer treated by surgery

Filippo Bellati*, Innocenza Palaia, Maria Luisa Gasparri, Angela Musella and Pierluigi Benedetti Panici

Author affiliations

Department of Gynecology and Obstetrics, “Sapienza” University of Rome, Viale Regina Elena 324, 00161, Rome, Italy

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Citation and License

BMC Cancer 2012, 12:479  doi:10.1186/1471-2407-12-479

Published: 17 October 2012



Breast cancer is a leading cause of death in developed countries. This neoplasm frequently relapses at distant sites such as bone, lung, pleura, brain and liver but rarely in the lower female genital tract.

Case presentation

We present the first case of isolated vaginal breast cancer metastasis and its surgical treatment.


This case report focuses on the importance of an accurate genital tract examination as part of regular follow up in breast cancer survivors. Indeed, after this experience we feel that surgery could be considered a valid option for the treatment of an isolated vaginal metastasis.

Breast cancer; Radical surgery; Vaginal metastasis