Table 2

Hazard ratios of gastric cancer incidence according to alcohol consumption
Alcohol category No. of cases Person-years Incidence rate/10,000 person-years HR (95% CI)a HR (95% CI)b
Follow-up from 1978 through 2008
Frequency
Non-drinkers 11 10,761 10.2 0.95 (0.47–1.92) 0.96 (0.47– 1.93)
A few times per year 27 24,948 10.8 1 (reference) 1 (reference)
1–4 times per month 132 94,719 13.9 1.37 (0.90–2.08) 1.27 (0.83–1.94)
2–7 times per week 15 6,759 22.2 2.19 (1.16–4.13) 2.00 (1.04–3.82)
p-trendc 0.11
Ethanol intake
Non-drinkers 11 10,761 10.2 0.94 (0.47–1.89) 0.95 (0.47–1.90)
0.1–9.9 g/week 29 26,574 10.9 1 (reference) 1 (reference)
10.0–24.9 g/week 56 48,660 11.5 1.10 (0.70–1.72) 1.04 (0.66–1.64)
25.0–99.9 g/week 56 34,858 16.1 1.57 (1.00–2.46) 1.44 (0.91–2.29)
≥100.0 g/week 33 16,334 20.2 2.07 (1.26–3.42) 1.90 (1.13–3.18)
Continuous, per 1 SD (90 g/week)c 1.12 (1.00–1.25)
Follow-up from 1993 through 2008
Frequency
Non-drinkers 7 9,676 7.2 1.32 (0.52–3.30) 1.34 (0.53–3.36)
A few times per year 13 23,282 5.6 1 (reference) 1 (reference)
1–4 times per month 79 86,369 9.2 1.88 (1.04–3.39) 1.81 (1.00–3.29)
2–7 times per week 11 5,917 18.6 3.95 (1.76–8.84) 3.99 (1.75–9.11)
p-trendc 0.007
Ethanol intake
Non-drinkers 7 9,676 7.2 1.20 (0.49–2.95) 1.23 (0.50–3.01)
0.1–9.9 g/week 15 24,707 6.1 1 (reference) 1 (reference)
10.0–24.9 g/week 32 44,576 7.2 1.32 (0.71–2.44) 1.29 (0.69–2.39)
25.0–99.9 g/week 36 31,626 11.4 2.13 (1.16–3.88) 2.06 (1.11–3.81)
≥100.0 g/week 20 14,658 13.6 2.74 (1.40–5.36) 2.74 (1.37–5.49)
Continuous, per 1 SD (90 g/week)c 1.17 (1.03–1.32)

aStratified by study. Age was used as the underlying time metric for all analyses.

bStratified by study and adjusted for smoking (never, former, ≤10 cig/day, 11–19 cig/day, ≥20 cig/day); education (primary, unfinished secondary, secondary, higher); BMI. Age was used as the underlying time metric for all analyses.

cTest for trend was carried out after exclusion of non-drinkers.

Everatt et al.

Everatt et al. BMC Cancer 2012 12:475   doi:10.1186/1471-2407-12-475

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